Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   APV63_RS00205 Genome accession   NZ_CP012905
Coordinates   37688..38431 (+) Length   247 a.a.
NCBI ID   WP_060472762.1    Uniprot ID   -
Organism   Helicobacter pylori strain 7C     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32688..43431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APV63_RS00180 (APV63_00175) panD 34855..35208 (+) 354 WP_060472759.1 aspartate 1-decarboxylase -
  APV63_RS00185 (APV63_00180) - 35211..35504 (+) 294 WP_000347915.1 YbaB/EbfC family nucleoid-associated protein -
  APV63_RS00190 (APV63_00185) - 35504..36499 (+) 996 WP_060472760.1 PDZ domain-containing protein -
  APV63_RS00195 (APV63_00190) comB6 36507..37562 (+) 1056 WP_060472761.1 type IV secretion system protein Machinery gene
  APV63_RS00200 (APV63_00195) comB7 37578..37691 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  APV63_RS00205 (APV63_00200) comB8 37688..38431 (+) 744 WP_060472762.1 type IV secretion system protein Machinery gene
  APV63_RS00210 (APV63_00205) comB9 38431..39408 (+) 978 WP_060472763.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  APV63_RS00215 (APV63_00210) comB10 39401..40537 (+) 1137 WP_060472764.1 DNA type IV secretion system protein ComB10 Machinery gene
  APV63_RS00220 (APV63_00215) - 40607..42019 (+) 1413 WP_060472765.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  APV63_RS00225 (APV63_00220) gmd 42074..43219 (+) 1146 WP_060472766.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28680.87 Da        Isoelectric Point: 8.9604

>NTDB_id=158165 APV63_RS00205 WP_060472762.1 37688..38431(+) (comB8) [Helicobacter pylori strain 7C]
MREKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKAQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLTNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=158165 APV63_RS00205 WP_060472762.1 37688..38431(+) (comB8) [Helicobacter pylori strain 7C]
ATGAGAGAAAAGCCTTTCAACAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGGCTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCCCTTGTTTTAGCGATCGTTTTAATCAGCATTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAATCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAGCCCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCCATTGCGGCTAAACTAACGAACGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.571

100

0.976

Multiple sequence alignment