Detailed information NTG0157692

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: SanJ4211_RS02545
• Genome accession: NZ_CP012805
• Coordinates: 497554..498168 (+)
• Length: 204 a.a.
• NCBI ID: WP_223349572.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain J4211
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 492554..503168

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4211_RS02535 (SanJ4211_0479)	mgtA	494085..496739 (+)	2655	WP_003025641.1	magnesium-translocating P-type ATPase	-
SanJ4211_RS02540 (SanJ4211_0480)	upp	496837..497466 (+)	630	WP_003025639.1	uracil phosphoribosyltransferase	-
SanJ4211_RS02545 (SanJ4211_0481)	clpP	497554..498168 (+)	615	WP_223349572.1	ATP-dependent Clp protease proteolytic subunit	Regulator
SanJ4211_RS02550 (SanJ4211_0482)	-	498260..498529 (+)	270	WP_003025630.1	DUF2129 domain-containing protein	-
SanJ4211_RS02555 (SanJ4211_0483)	-	498612..499775 (+)	1164	WP_003025628.1	ABC transporter substrate-binding protein	-
SanJ4211_RS02560 (SanJ4211_0485)	-	500163..501032 (+)	870	WP_024052038.1	branched-chain amino acid ABC transporter permease	-
SanJ4211_RS02565 (SanJ4211_0486)	-	501036..501986 (+)	951	WP_021001401.1	branched-chain amino acid ABC transporter permease	-
SanJ4211_RS02570 (SanJ4211_0487)	-	501986..502750 (+)	765	WP_021001402.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 204 a.a.
• Molecular weight: 22503.62 Da
• Isoelectric Point: 4.6199

>NTDB_id=157692 SanJ4211_RS02545 WP_223349572.1 497554..498168(+) (clpP) [Streptococcus anginosus strain J4211]
MSDEKENTMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINTPGGSVSAG
LAIVDTMNFIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGSGTQQTDMAIAAEHLLKTRNNLEK
ILADNSGKTIKQVHKDAERDYWMSAQETLDYGFIDEIMANNNLN

Nucleotide

• Length: 615 bp

>NTDB_id=157692 SanJ4211_RS02545 WP_223349572.1 497554..498168(+) (clpP) [Streptococcus anginosus strain J4211]
ATATCAGATGAAAAGGAGAATACAATGATTCCTGTAGTTATTGAACAAACAAGTCGTGGGGAACGTTCCTACGATATTTA
CTCACGCTTATTAAAAGATCGCATTATTATGCTGACAGGTCCTGTTGAGGACAATATGGCTAATTCTATTATTGCGCAAT
TGCTTTTCCTTGATGCACAAGATAATACTAAAGATATTTATCTTTACATCAATACGCCAGGAGGTTCTGTATCGGCGGGT
CTAGCGATTGTCGATACCATGAACTTCATCAAATCAGATGTTCAAACAATTGTCATGGGGATGGCTGCTTCCATGGGAAC
TATTATTGCTTCAAGCGGTGCTAAAGGCAAACGCTTCATGTTGCCGAATGCAGAATACTTGATTCACCAACCAATGGGTG
GAACTGGTAGCGGTACGCAACAAACCGATATGGCGATTGCAGCTGAGCATTTGCTGAAAACTCGGAATAACTTGGAGAAA
ATCCTTGCGGATAATTCAGGGAAAACCATTAAGCAAGTACATAAAGACGCAGAACGCGATTATTGGATGAGCGCTCAAGA
AACCTTGGATTATGGTTTCATTGATGAAATTATGGCAAATAATAATTTAAACTAG

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (19-200)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	89.655	99.51	0.892
clpP	Streptococcus thermophilus LMD-9	92.308	95.588	0.882
clpP	Streptococcus thermophilus LMG 18311	92.308	95.588	0.882
clpP	Streptococcus pyogenes JRS4	91.795	95.588	0.877
clpP	Streptococcus pyogenes MGAS315	91.795	95.588	0.877
clpP	Streptococcus pneumoniae D39	90.816	96.078	0.873
clpP	Streptococcus pneumoniae Rx1	90.816	96.078	0.873
clpP	Streptococcus pneumoniae R6	90.816	96.078	0.873
clpP	Streptococcus pneumoniae TIGR4	90.816	96.078	0.873
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.667	95.588	0.828
clpP	Lactococcus lactis subsp. cremoris KW2	86.154	95.588	0.824
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	94.608	0.539
clpP	Bacillus subtilis subsp. subtilis str. 168	56.25	94.118	0.529