Detailed information NTG0157350

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: AN924_RS04595
• Genome accession: NZ_CP012731
• Coordinates: 935650..935931 (-)
• Length: 93 a.a.
• NCBI ID: WP_009909092.1
• Uniprot ID: A0A116MYU4
• Organism: Streptococcus suis strain 90-1330
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 930650..940931

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AN924_RS04560 (AN924_09610)	-	931030..931626 (-)	597	WP_009909104.1	folate family ECF transporter S component	-
AN924_RS04565 (AN924_09620)	-	931941..933128 (-)	1188	WP_013730078.1	acetate kinase	-
AN924_RS04570 (AN924_09630)	comYH	933178..934131 (-)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
AN924_RS04575 (AN924_09640)	comGG	934188..934598 (-)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
AN924_RS04580 (AN924_09650)	comGF/cglF	934576..935010 (-)	435	WP_009909097.1	competence type IV pilus minor pilin ComGF	Machinery gene
AN924_RS04585 (AN924_09660)	comYE	934997..935290 (-)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
AN924_RS04590 (AN924_09670)	comGD	935262..935669 (-)	408	WP_009909093.1	competence type IV pilus minor pilin ComGD	-
AN924_RS04595 (AN924_09680)	comYC	935650..935931 (-)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
AN924_RS04600 (AN924_09690)	comYB	935933..936970 (-)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
AN924_RS04605 (AN924_09700)	comYA	936882..937832 (-)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
AN924_RS04610 (AN924_09710)	-	937918..938868 (+)	951	WP_002936565.1	S66 family peptidase	-
AN924_RS04615 (AN924_09720)	-	938903..939268 (-)	366	WP_002936568.1	DUF1033 family protein	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10320.28 Da
• Isoelectric Point: 8.4284

>NTDB_id=157350 AN924_RS04595 WP_009909092.1 935650..935931(-) (comYC) [Streptococcus suis strain 90-1330]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDKEATVADLQAAGYI
TEKQAKQYAAAKK

Nucleotide

• Length: 282 bp

>NTDB_id=157350 AN924_RS04595 WP_009909092.1 935650..935931(-) (comYC) [Streptococcus suis strain 90-1330]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGCCAGATGGAGCTCTATGAATTGGAACATGACAAGGAAGCAACGGTGGCAGACTTGCAGGCAGCTGGCTACATC
ACTGAAAAACAAGCAAAACAGTATGCTGCGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A116MYU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	96.774	100	0.968
comGC/cglC	Streptococcus mitis SK321	67.059	91.398	0.613
comGC/cglC	Streptococcus mitis NCTC 12261	67.059	91.398	0.613
comYC	Streptococcus gordonii str. Challis substr. CH1	62.637	97.849	0.613
comGC/cglC	Streptococcus pneumoniae R6	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae D39	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae TIGR4	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae Rx1	69.136	87.097	0.602
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	57.955	94.624	0.548
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398