Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RN86_RS08715 Genome accession   NZ_CP012648
Coordinates   1795016..1796416 (-) Length   466 a.a.
NCBI ID   WP_053794630.1    Uniprot ID   -
Organism   Streptococcus gordonii strain KCOM 1506 (= ChDC B679)     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1790016..1801416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN86_RS08690 (RN86_08695) - 1790418..1791011 (-) 594 WP_053794626.1 class I SAM-dependent methyltransferase -
  RN86_RS08695 (RN86_08700) coaA 1791117..1792037 (+) 921 WP_053794627.1 type I pantothenate kinase -
  RN86_RS08700 (RN86_08705) rpsT 1792134..1792382 (+) 249 WP_008808726.1 30S ribosomal protein S20 -
  RN86_RS08705 (RN86_08710) - 1792613..1794064 (+) 1452 WP_053794628.1 alpha-amylase -
  RN86_RS08710 (RN86_08715) - 1794088..1795014 (-) 927 WP_053794629.1 2-dehydropantoate 2-reductase N-terminal domain-containing protein -
  RN86_RS08715 (RN86_08720) ciaH 1795016..1796416 (-) 1401 WP_053794630.1 HAMP domain-containing sensor histidine kinase Regulator
  RN86_RS08720 (RN86_08725) ciaR 1796406..1797080 (-) 675 WP_008808730.1 response regulator transcription factor Regulator
  RN86_RS08725 (RN86_08730) - 1797211..1797666 (-) 456 WP_053794631.1 hypothetical protein -
  RN86_RS08730 (RN86_08735) - 1797878..1798420 (+) 543 WP_053794632.1 biotin transporter BioY -
  RN86_RS11630 - 1798568..1798831 (+) 264 Protein_1687 ISL3 family transposase -
  RN86_RS08735 (RN86_08740) - 1798834..1799649 (-) 816 WP_053794633.1 SDR family NAD(P)-dependent oxidoreductase -
  RN86_RS08740 (RN86_08745) - 1799653..1799979 (-) 327 WP_053794634.1 multidrug efflux SMR transporter -
  RN86_RS08745 (RN86_08750) - 1800036..1800320 (-) 285 WP_002917391.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 466 a.a.        Molecular weight: 53043.10 Da        Isoelectric Point: 9.4613

>NTDB_id=156104 RN86_RS08715 WP_053794630.1 1795016..1796416(-) (ciaH) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MLNKLRRTFYADDFSYFIRYFGVFTLIFSAMTLLIIQIMRSGLYTTVDDNLKSLSQNPRSVLHLALARAANMQPTIDEGQ
SSDDVSGPQDAPDPGPMDNLKVNSNTEAVLFDEDLKPLTTADHFLSLKKISIKKKDVGKIIQTTLKNNYGQEELYRMLVF
EINPSEFLSGNLLNKVKYAAVLINVNQLEQTSQNHEQIIVIVMISFWLISIIASIYLARVSVKPLMDSMQKQKSFVENAS
HELRTPLAVLQNRLETLFRKPEATIMESSENIASSLEEVRNMRMLTTNLLNLARRDDGIKAEIAEVEPEFFTTTFANYEI
IADENEKVFVFENHINHNIKTDRTLLKQLMTILFDNAVKYTEEDGVIKFIVWSKDRSLYLRVSDNGPGINNEDKKKIFDR
FYRVDKARTRQKGGFGLGLSLAKQIADALKGTITVKDNRPKGTIFEVKISIKSESKKKSTKLIGNK

Nucleotide


Download         Length: 1401 bp        

>NTDB_id=156104 RN86_RS08715 WP_053794630.1 1795016..1796416(-) (ciaH) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGCTGAATAAACTTAGACGAACTTTTTATGCGGATGATTTTTCATATTTCATTCGCTATTTTGGTGTATTCACACTGAT
TTTCTCGGCCATGACTCTTTTAATCATTCAGATTATGCGCTCAGGACTCTATACAACCGTTGACGATAATTTAAAAAGTT
TAAGTCAGAATCCCAGATCTGTTCTCCACCTTGCTTTGGCTCGTGCAGCCAATATGCAACCGACGATTGATGAAGGTCAG
TCATCTGATGATGTATCTGGACCACAAGACGCACCAGACCCTGGACCAATGGATAATCTGAAGGTGAATTCGAACACTGA
AGCTGTCTTGTTTGATGAAGACTTGAAACCATTGACTACTGCAGATCATTTTCTTAGTTTAAAAAAGATTTCAATCAAGA
AAAAGGATGTAGGTAAAATTATTCAGACTACTTTGAAAAACAACTATGGTCAAGAAGAACTCTATCGTATGTTGGTTTTT
GAAATTAATCCAAGCGAATTCTTATCTGGGAATCTTTTGAACAAAGTTAAATATGCAGCAGTCCTGATTAATGTCAATCA
GTTGGAGCAAACCAGTCAGAATCATGAACAGATTATTGTCATTGTTATGATTAGCTTTTGGTTAATCTCAATTATTGCTA
GTATCTATTTGGCTCGTGTCAGTGTGAAGCCTCTGATGGATAGTATGCAGAAACAAAAATCTTTTGTTGAAAATGCAAGC
CATGAGTTGCGTACTCCTTTAGCCGTTTTGCAAAACCGCTTGGAAACTCTTTTCCGAAAACCCGAAGCTACCATTATGGA
ATCAAGCGAAAATATTGCCTCCAGTCTGGAAGAAGTTCGGAATATGCGGATGCTAACAACTAATCTATTGAATCTTGCAA
GAAGAGATGATGGCATTAAGGCTGAAATTGCTGAAGTTGAACCAGAATTTTTCACTACAACATTTGCCAACTACGAAATT
ATTGCTGATGAAAACGAGAAAGTATTTGTCTTCGAAAACCATATTAACCACAATATCAAGACAGACAGAACACTTCTAAA
ACAGCTGATGACCATTCTCTTTGATAATGCTGTAAAATATACGGAAGAAGATGGGGTTATTAAGTTTATAGTATGGTCAA
AAGACCGTTCTCTTTACTTACGAGTGTCTGATAACGGACCTGGAATCAATAATGAAGACAAAAAGAAAATTTTTGATCGT
TTTTATAGGGTTGATAAAGCCAGAACAAGACAAAAGGGTGGTTTTGGTCTAGGTCTATCCCTTGCAAAACAAATTGCCGA
TGCTCTAAAGGGTACAATTACTGTTAAAGATAATAGACCGAAAGGTACCATTTTTGAAGTCAAAATTTCCATTAAATCAG
AAAGCAAGAAAAAATCAACTAAGCTAATAGGAAATAAATGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(342-449)

His Kinase A (phospho-acceptor) domain (HisKA)

(233-298)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

66.594

98.283

0.655
  ciaH Streptococcus pneumoniae D39

66.594

98.283

0.655
  ciaH Streptococcus pneumoniae R6

66.594

98.283

0.655
  ciaH Streptococcus pneumoniae TIGR4

66.594

98.283

0.655
  ciaH Streptococcus mutans UA159

54.566

96.352

0.526

Multiple sequence alignment