Detailed information NTG0155437

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: A7329_RS24800
• Genome accession: NZ_CP012582
• Coordinates: 5384292..5385629 (+)
• Length: 445 a.a.
• NCBI ID: WP_003110427.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain PA_D21
• Function: regulate pilin expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	5385675..5393799	5384292..5385629	flank	46

Gene organization within MGE regions

Location: 5384292..5393799

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7329_RS24800 (A7329_24800)	pilR	5384292..5385629 (+)	1338	WP_003110427.1	two-component system response regulator PilR	Regulator
A7329_RS24805 (A7329_24805)	thiO	5385675..5386769 (-)	1095	WP_033944813.1	glycine oxidase ThiO	-
A7329_RS24810 (A7329_24810)	-	5386909..5387409 (+)	501	WP_016254062.1	GspH/FimT family pseudopilin	-
A7329_RS24815 (A7329_24815)	-	5387532..5388020 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
A7329_RS24820 (A7329_24820)	pilV	5388030..5388554 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
A7329_RS24825 (A7329_24825)	-	5388563..5389378 (+)	816	WP_034027589.1	PilW family protein	-
A7329_RS24830 (A7329_24830)	-	5389375..5389980 (+)	606	WP_003116263.1	pilus assembly PilX family protein	-
A7329_RS24835 (A7329_24835)	-	5389994..5393470 (+)	3477	WP_034027586.1	pilus assembly protein	-
A7329_RS24840 (A7329_24840)	-	5393473..5393799 (+)	327	WP_016254060.1	PilY2 family type 4a fimbrial biogenesis protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49723.03 Da
• Isoelectric Point: 5.8638

>NTDB_id=155437 A7329_RS24800 WP_003110427.1 5384292..5385629(+) (pilR) [Pseudomonas aeruginosa strain PA_D21]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLADRI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=155437 A7329_RS24800 WP_003110427.1 5384292..5385629(+) (pilR) [Pseudomonas aeruginosa strain PA_D21]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGCCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCTACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGATCGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGATATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Response regulator receiver domain (Response_reg) (7-115)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	99.775	100	0.998
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384