Detailed information NTG0154597

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: AMM49_RS04265
• Genome accession: NZ_CP012480
• Coordinates: 806759..808996 (+)
• Length: 745 a.a.
• NCBI ID: WP_000902956.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain NGBS128
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 801759..813996

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AMM49_RS04240 (AMM49_04235)	-	802355..803941 (+)	1587	WP_060914831.1	DEAD/DEAH box helicase	-
AMM49_RS04245 (AMM49_04240)	-	804124..804390 (-)	267	WP_000598735.1	GIY-YIG nuclease family protein	-
AMM49_RS04250 (AMM49_04245)	-	804383..805147 (-)	765	WP_000567428.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
AMM49_RS04255 (AMM49_04250)	-	805282..806022 (+)	741	WP_000500222.1	lysophospholipid acyltransferase family protein	-
AMM49_RS04260 (AMM49_04255)	-	806122..806775 (+)	654	WP_000461741.1	helix-hairpin-helix domain-containing protein	-
AMM49_RS04265 (AMM49_04260)	comEC/celB	806759..808996 (+)	2238	WP_000902956.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AMM49_RS04270 (AMM49_04265)	-	809122..809931 (+)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
AMM49_RS04275 (AMM49_04270)	-	809942..810886 (+)	945	WP_000200834.1	LacI family DNA-binding transcriptional regulator	-
AMM49_RS04280 (AMM49_04275)	-	810945..811937 (-)	993	WP_000800989.1	alpha/beta hydrolase fold domain-containing protein	-
AMM49_RS04285 (AMM49_04280)	-	812113..812841 (+)	729	WP_000468967.1	methyltransferase domain-containing protein	-
AMM49_RS04290 (AMM49_04285)	holA	812895..813932 (+)	1038	WP_000560298.1	DNA polymerase III subunit delta	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85666.56 Da
• Isoelectric Point: 9.8125

>NTDB_id=154597 AMM49_RS04265 WP_000902956.1 806759..808996(+) (comEC/celB) [Streptococcus agalactiae strain NGBS128]
MLHLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFTFIFLIYQYDRETIFKTITIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIKVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLFQHRSFFDLMFKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPFVKLSCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDNLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKRLSKIGVAVKSIEAGDKLSVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=154597 AMM49_RS04265 WP_000902956.1 806759..808996(+) (comEC/celB) [Streptococcus agalactiae strain NGBS128]
ATGTTACACTTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTACTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAACAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTAAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTACACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATAATTGCAGATATCAAACTTGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATTTCAACATAGGTCTTTCTT
TGATCTTATGTTTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCTCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCACCGTTCGTTAAATTAAGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTATTATTAAAATGGAC
TGGGCAACTGTTTCCAAGACCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAAGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAACCAGTCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATAATTTAGTGATAACTCATACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCGTTTATCAAAGATAGGAGTAGCTGTAAAATCTATAGAAGCTGGTGATAAACTTTCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTGTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.262	100	0.485
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus pneumoniae TIGR4	46.791	100	0.47
comEC/celB	Streptococcus pneumoniae Rx1	46.319	100	0.464
comEC/celB	Streptococcus pneumoniae D39	46.319	100	0.464
comEC/celB	Streptococcus pneumoniae R6	46.319	100	0.464
comEC	Lactococcus lactis subsp. cremoris KW2	44.355	99.866	0.443