Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A7327_RS09830 Genome accession   NZ_CP015646
Coordinates   2009398..2010021 (-) Length   207 a.a.
NCBI ID   WP_001045131.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 08-02300     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2004398..2015021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7327_RS09805 (A7327_09800) - 2004783..2005979 (-) 1197 WP_000238227.1 metallophosphoesterase family protein -
  A7327_RS09810 (A7327_09805) - 2006270..2006368 (-) 99 WP_001802255.1 hypothetical protein -
  A7327_RS09815 (A7327_09810) - 2006862..2007206 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  A7327_RS09820 (A7327_09815) - 2007275..2008399 (-) 1125 WP_000992523.1 DUF445 domain-containing protein -
  A7327_RS09825 (A7327_09820) xdrA 2008578..2009042 (-) 465 WP_000375864.1 XRE family transcriptional regulator XdrA -
  A7327_RS09830 (A7327_09825) vraR 2009398..2010021 (-) 624 WP_001045131.1 response regulator Regulator
  A7327_RS09835 (A7327_09830) - 2010043..2011155 (-) 1113 WP_000437970.1 GAF domain-containing sensor histidine kinase -
  A7327_RS09840 (A7327_09835) - 2011318..2012139 (+) 822 WP_000669373.1 RluA family pseudouridine synthase -
  A7327_RS09845 (A7327_09840) fumC 2012592..2013977 (-) 1386 WP_000116230.1 class II fumarate hydratase -
  A7327_RS09850 (A7327_09845) - 2014173..2014568 (-) 396 WP_000901023.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23909.59 Da        Isoelectric Point: 5.5730

>NTDB_id=154562 A7327_RS09830 WP_001045131.1 2009398..2010021(-) (vraR) [Staphylococcus aureus strain 08-02300]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDIEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=154562 A7327_RS09830 WP_001045131.1 2009398..2010021(-) (vraR) [Staphylococcus aureus strain 08-02300]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACAT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATTGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-201)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

100

0.406
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.377
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362