Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   AKO63_RS18315 Genome accession   NZ_CP012379
Coordinates   3576573..3577697 (-) Length   374 a.a.
NCBI ID   WP_000228508.1    Uniprot ID   A0A0D8VMA7
Organism   Escherichia coli strain PAR     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 3574157..3583655 3576573..3577697 within 0


Gene organization within MGE regions


Location: 3574157..3583655
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AKO63_RS18295 (AKO63_3531) aroE 3574157..3574975 (-) 819 WP_094058292.1 shikimate dehydrogenase -
  AKO63_RS18300 (AKO63_3532) tsaC 3574980..3575552 (-) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  AKO63_RS18305 yrdD 3575557..3576099 (-) 543 WP_001312137.1 type I DNA topoisomerase -
  AKO63_RS18310 (AKO63_3533) smg 3576128..3576601 (-) 474 WP_000460672.1 DUF494 family protein Smg -
  AKO63_RS18315 (AKO63_3534) dprA 3576573..3577697 (-) 1125 WP_000228508.1 DNA-protecting protein DprA Machinery gene
  AKO63_RS18320 (AKO63_3535) def 3577827..3578336 (+) 510 WP_000114984.1 peptide deformylase -
  AKO63_RS18325 (AKO63_3536) fmt 3578351..3579298 (+) 948 WP_000004421.1 methionyl-tRNA formyltransferase -
  AKO63_RS18330 (AKO63_3537) rsmB 3579350..3580639 (+) 1290 WP_000744766.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  AKO63_RS18335 (AKO63_3538) trkA 3580661..3582037 (+) 1377 WP_001539892.1 Trk system potassium transporter TrkA -
  AKO63_RS18340 (AKO63_3539) mscL 3582167..3582580 (+) 414 WP_000022450.1 large-conductance mechanosensitive channel protein MscL -
  AKO63_RS18345 arfA 3582577..3582795 (-) 219 WP_000092695.1 alternative ribosome-rescue factor ArfA -
  AKO63_RS18350 (AKO63_3540) zntR 3582851..3583276 (-) 426 WP_000285610.1 Zn(2+)-responsive transcriptional regulator -
  AKO63_RS18355 (AKO63_3541) yhdN 3583287..3583655 (-) 369 WP_000266504.1 DUF1992 domain-containing protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40892.82 Da        Isoelectric Point: 6.0395

>NTDB_id=153988 AKO63_RS18315 WP_000228508.1 3576573..3577697(-) (dprA) [Escherichia coli strain PAR]
MVDTEIWLRLISISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=153988 AKO63_RS18315 WP_000228508.1 3576573..3577697(-) (dprA) [Escherichia coli strain PAR]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATTAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (DprA_WH)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D8VMA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

43.917

90.107

0.396
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39

Multiple sequence alignment