Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   A5480_RS06360 Genome accession   NZ_CP015343
Coordinates   1401759..1402436 (-) Length   225 a.a.
NCBI ID   WP_011213604.1    Uniprot ID   -
Organism   Legionella pneumophila strain D-7631     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1396759..1407436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A5480_RS06335 (A5480_06335) - 1398071..1398814 (+) 744 WP_027224095.1 YebC/PmpR family DNA-binding transcriptional regulator -
  A5480_RS06340 (A5480_06340) ruvC 1398814..1399338 (+) 525 WP_027224094.1 crossover junction endodeoxyribonuclease RuvC -
  A5480_RS06345 (A5480_06345) ruvA 1399335..1399934 (+) 600 WP_011213600.1 Holliday junction branch migration protein RuvA -
  A5480_RS06350 (A5480_06350) - 1399986..1400306 (+) 321 WP_011946343.1 hypothetical protein -
  A5480_RS06355 (A5480_06355) - 1400347..1401762 (-) 1416 WP_010947022.1 ATP-binding protein -
  A5480_RS06360 (A5480_06360) ciaR 1401759..1402436 (-) 678 WP_011213604.1 response regulator Regulator
  A5480_RS06365 (A5480_06365) - 1402497..1403042 (-) 546 WP_011215337.1 septation protein A -
  A5480_RS06370 (A5480_06370) - 1403286..1404725 (-) 1440 WP_027224093.1 lytic transglycosylase -
  A5480_RS06380 (A5480_06380) gloB 1404839..1405603 (-) 765 WP_011213607.1 hydroxyacylglutathione hydrolase -
  A5480_RS06385 (A5480_06385) - 1405607..1406455 (-) 849 WP_027224091.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  A5480_RS06390 (A5480_06390) - 1406732..1406941 (+) 210 WP_011213609.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25151.74 Da        Isoelectric Point: 4.9981

>NTDB_id=153303 A5480_RS06360 WP_011213604.1 1401759..1402436(-) (ciaR) [Legionella pneumophila strain D-7631]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide


Download         Length: 678 bp        

>NTDB_id=153303 A5480_RS06360 WP_011213604.1 1401759..1402436(-) (ciaR) [Legionella pneumophila strain D-7631]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTACGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTAGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGGGAATCAATAGAAGATAGAGTAAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTGGTAAGACGCTCTCAGGGCAGAGCTGATTCCGTGTTGCAATATAAAAATATTACTC
TCGATCCTGCTGCTCATTCTGTATTCGTTGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTGCAGAAA
CTACTTGAAAACAGTGGTCAGGTCTTATCTCGAGAACAATTAATGCAGAGTATTTATGGTTGGGAAGAAGACGTGGACAG
TAATGCTCTCGAAGTTCATATCCATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-215)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae D39

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae R6

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae TIGR4

38.356

97.333

0.373
  ciaR Streptococcus mutans UA159

37.9

97.333

0.369
  micA Streptococcus pneumoniae Cp1015

35.345

100

0.364