Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   A4U84_RS03670 Genome accession   NZ_CP015099
Coordinates   792178..792849 (-) Length   223 a.a.
NCBI ID   WP_021119362.1    Uniprot ID   -
Organism   Glaesserella parasuis strain SC1401     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 787178..797849
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4U84_RS03655 (A4U84_03655) groL 788362..790005 (-) 1644 WP_062924024.1 chaperonin GroEL -
  A4U84_RS03660 (A4U84_03660) - 790116..790403 (-) 288 WP_005713186.1 co-chaperone GroES -
  A4U84_RS12180 - 790610..790672 (-) 63 Protein_716 RNA-guided endonuclease TnpB family protein -
  A4U84_RS03665 (A4U84_03665) qseC 790794..792191 (-) 1398 WP_062924025.1 quorum sensing histidine kinase QseC -
  A4U84_RS03670 (A4U84_03670) ciaR 792178..792849 (-) 672 WP_021119362.1 response regulator Regulator
  A4U84_RS03675 (A4U84_03675) - 792910..793275 (-) 366 WP_021114421.1 YgiW/YdeI family stress tolerance OB fold protein -
  A4U84_RS03680 (A4U84_03680) - 793444..795405 (-) 1962 WP_062924026.1 TonB-dependent receptor domain-containing protein -
  A4U84_RS03685 (A4U84_03685) rpmG 795560..795730 (-) 171 WP_005624479.1 50S ribosomal protein L33 -
  A4U84_RS03690 (A4U84_03690) rpmB 795742..795978 (-) 237 WP_006251446.1 50S ribosomal protein L28 -
  A4U84_RS03695 (A4U84_03695) radC 796104..796820 (-) 717 WP_021113221.1 RadC family protein Machinery gene

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25484.17 Da        Isoelectric Point: 6.0355

>NTDB_id=151746 A4U84_RS03670 WP_021119362.1 792178..792849(-) (ciaR) [Glaesserella parasuis strain SC1401]
MRILLVEDDPLIGEGLKLGLSKSGFSVDWFADGRSGLEALSSAPYDAVVLDLTLPKMDGLEVLQSWRRANQDVPVLILTA
RDTLDERITGLQRGADDYLCKPFALAEVVARLQALIRRRYGHTNPVIEHSLVKFDPNQRKVFLREQEVTLTTREYNLLEL
FMHNKERVLTRSFIEEKLYTWDDEVSSNALEVHIYNLRQKLGKQFIRTVHSVGYALGKNDEVA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=151746 A4U84_RS03670 WP_021119362.1 792178..792849(-) (ciaR) [Glaesserella parasuis strain SC1401]
ATGCGTATTTTATTAGTTGAAGACGATCCGTTGATCGGTGAAGGGCTAAAACTTGGTTTGAGTAAATCTGGCTTTAGTGT
GGACTGGTTTGCCGATGGCAGATCTGGCTTAGAGGCGTTAAGTTCTGCTCCTTATGATGCCGTTGTTCTCGATCTCACCT
TGCCTAAAATGGACGGACTTGAGGTGTTACAAAGTTGGCGACGGGCAAATCAAGATGTGCCAGTGCTAATTTTGACTGCA
AGAGATACCCTTGATGAACGTATCACTGGGCTACAACGTGGTGCAGATGATTATCTTTGTAAACCTTTTGCTCTCGCAGA
AGTTGTAGCTCGTTTACAAGCTTTGATCCGCCGTCGTTATGGGCATACCAACCCCGTGATTGAACATAGTTTAGTTAAAT
TCGATCCAAACCAACGCAAAGTGTTTCTTCGGGAGCAAGAAGTCACCCTAACCACACGAGAGTACAATTTACTTGAGCTA
TTTATGCACAATAAAGAGCGTGTTCTCACCCGTTCTTTTATTGAAGAGAAACTCTATACTTGGGACGATGAAGTCAGTAG
CAACGCCCTTGAAGTCCATATCTACAATTTACGCCAAAAACTCGGAAAACAGTTTATTCGTACCGTACACAGTGTTGGCT
ATGCCTTAGGAAAAAACGATGAAGTTGCTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.123

100

0.368
  ciaR Streptococcus pneumoniae D39

36.123

100

0.368
  ciaR Streptococcus pneumoniae R6

36.123

100

0.368
  ciaR Streptococcus pneumoniae TIGR4

36.123

100

0.368
  ciaR Streptococcus mutans UA159

35.526

100

0.363