Detailed information NTG0151024

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: ADJ80_RS03665
• Genome accession: NZ_CP012067
• Coordinates: 745158..746582 (-)
• Length: 474 a.a.
• NCBI ID: WP_050692985.1
• Uniprot ID: -
• Organism: Aggregatibacter aphrophilus strain W10433
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 740158..751582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ADJ80_RS03640 (ADJ80_03655)	ygiD	740689..741474 (+)	786	WP_080988233.1	4,5-DOPA dioxygenase extradiol	-
ADJ80_RS03645 (ADJ80_03660)	-	741754..742122 (-)	369	WP_005701820.1	rhodanese-like domain-containing protein	-
ADJ80_RS03650 (ADJ80_03665)	-	742446..743300 (-)	855	WP_050692982.1	Dam family site-specific DNA-(adenine-N6)-methyltransferase	-
ADJ80_RS03655 (ADJ80_03670)	aroB	743306..744394 (-)	1089	WP_050692983.1	3-dehydroquinate synthase	-
ADJ80_RS03660 (ADJ80_03675)	aroK	744416..744943 (-)	528	WP_050692984.1	shikimate kinase AroK	-
ADJ80_RS03665 (ADJ80_03680)	comE	745158..746582 (-)	1425	WP_050692985.1	type IV pilus secretin PilQ	Machinery gene
ADJ80_RS03670 (ADJ80_03685)	-	746592..746987 (-)	396	WP_005701815.1	hypothetical protein	-
ADJ80_RS03675 (ADJ80_03690)	-	746987..747520 (-)	534	WP_005701814.1	competence protein	-
ADJ80_RS03680 (ADJ80_03695)	-	747517..748035 (-)	519	WP_005701813.1	PilN domain-containing protein	-
ADJ80_RS03685 (ADJ80_03700)	-	748049..748852 (-)	804	WP_050692986.1	hypothetical protein	-
ADJ80_RS03690 (ADJ80_03705)	-	748979..751540 (+)	2562	WP_050692987.1	penicillin-binding protein 1A	-

Sequence

Protein

• Length: 474 a.a.
• Molecular weight: 52237.14 Da
• Isoelectric Point: 7.0239

>NTDB_id=151024 ADJ80_RS03665 WP_050692985.1 745158..746582(-) (comE) [Aggregatibacter aphrophilus strain W10433]
MKLPLPYCVKCGLFFSCFLSFAISLSVHAEQNQVFSIRLKQAPLVPTLQQLALAQNVNLIIDDELQGTVSLQLENVDLDQ
LFRSVAKIKQLDLWQENGIYYLSKLDTSAKFATKMDEPFILPAVMTEEPTRLTTATIKLHFAKASEVMKSLTGGSGSLLS
PNGSLTFDDRSNLLLIQDEPKSIANLKKLIKELDKPIEQIAIEARIVTMNGESLKELGVRWGIFNPTENAHRIGGSLAGN
GFDNITNQLNVNFPTATTPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKAASIKQGTELPYILVNEK
SGSQSVEFREAVLGLEVTPHISQDKQILLDLVVSQNAPGSRVAHGLGEVVSIDKQEINTQVFAKDGETIVLGGVFHDTIT
KNVDKVPLLGDIPGIKHLFSKESERHQKRELVIFVTPHILRQGETLESFKQKQGITQQTKMLPTQNTHKNPTKS

Nucleotide

• Length: 1425 bp

>NTDB_id=151024 ADJ80_RS03665 WP_050692985.1 745158..746582(-) (comE) [Aggregatibacter aphrophilus strain W10433]
ATGAAATTACCTCTGCCCTACTGCGTAAAGTGCGGTCTGTTTTTCAGTTGTTTTTTGAGTTTTGCCATAAGCCTTTCCGT
TCATGCGGAACAAAATCAAGTGTTTTCCATTCGGCTGAAACAAGCGCCCTTGGTGCCCACTTTGCAACAATTGGCGTTAG
CGCAAAACGTCAATTTGATTATTGATGACGAATTGCAAGGCACGGTTTCGCTCCAACTGGAAAACGTGGATTTAGATCAG
TTGTTTCGCTCCGTTGCTAAAATTAAGCAGTTGGATTTGTGGCAGGAAAATGGGATTTATTATTTAAGCAAACTCGATAC
TTCCGCTAAATTTGCCACCAAAATGGACGAACCCTTTATCCTTCCTGCCGTGATGACGGAAGAACCGACGCGACTCACCA
CCGCCACCATTAAATTGCATTTTGCTAAAGCCTCGGAAGTGATGAAATCACTCACCGGCGGTAGCGGTTCGTTACTTTCC
CCAAACGGTAGCCTCACTTTTGACGATCGCAGTAACTTGTTGTTAATTCAAGACGAACCGAAATCCATCGCTAACCTGAA
AAAGCTGATTAAAGAATTAGATAAGCCCATTGAACAAATCGCCATTGAAGCCAGAATTGTCACCATGAACGGTGAAAGTC
TAAAAGAATTGGGCGTACGCTGGGGCATTTTTAACCCCACCGAAAATGCACATCGTATCGGCGGAAGTTTGGCGGGTAAC
GGCTTTGACAATATCACCAATCAATTAAACGTCAACTTCCCTACAGCCACCACCCCCGCCGGTTCCGTCGCACTGCAGGT
GGCGAAAATCAACGGACGACTTTTAGACTTAGAATTGACCGCACTTGAACGGGAAAATAATGTAGAAATCATTGCCAGCC
CGCGATTGCTCACAACCAATAAAAAAGCCGCCAGCATCAAGCAAGGAACGGAATTGCCGTATATTTTGGTGAATGAAAAA
AGCGGCTCACAAAGCGTGGAATTTCGTGAGGCCGTGTTAGGCTTGGAAGTAACACCGCATATTTCACAAGATAAACAAAT
TCTGTTGGATTTAGTGGTCAGTCAAAATGCGCCCGGTAGCCGAGTAGCACATGGTTTGGGCGAAGTCGTCTCCATTGATA
AACAGGAAATCAACACCCAAGTCTTTGCTAAAGACGGAGAAACCATCGTGTTGGGTGGCGTATTTCACGATACCATCACT
AAAAACGTGGACAAAGTGCCCTTGTTGGGAGACATTCCGGGCATAAAACACTTGTTTAGCAAAGAAAGCGAACGTCATCA
AAAACGGGAATTGGTGATTTTCGTCACACCGCATATTTTACGCCAAGGAGAAACCTTAGAATCCTTTAAACAAAAACAGG
GCATAACACAGCAAACTAAAATGCTCCCCACACAAAACACGCATAAAAATCCAACAAAATCGTAG

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (281-441)

• Bacterial type II/III secretion system short domain (Secretin_N) (134-199)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	70.179	94.093	0.66
comE	Haemophilus influenzae 86-028NP	68.973	94.515	0.652
comE	Glaesserella parasuis strain SC1401	52.045	92.827	0.483
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	41.667	91.139	0.38
pilQ	Vibrio cholerae strain A1552	41.667	91.139	0.38
pilQ	Vibrio campbellii strain DS40M4	40.724	93.249	0.38