Detailed information NTG0149745

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: A1R12_RS18925
• Genome accession: NZ_CP014783
• Coordinates: 3920293..3921489 (-)
• Length: 398 a.a.
• NCBI ID: WP_022554034.1
• Uniprot ID: -
• Organism: Bacillus amyloliquefaciens strain B15
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3915293..3926489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A1R12_RS18905 (A1R12_18905)	-	3915621..3916943 (-)	1323	WP_061890921.1	hypothetical protein	-
A1R12_RS18910 (A1R12_18910)	-	3916940..3917947 (-)	1008	WP_031379194.1	ThiF family adenylyltransferase	-
A1R12_RS18915 (A1R12_18915)	-	3918179..3919597 (-)	1419	WP_039253191.1	sensor histidine kinase	-
A1R12_RS18920 (A1R12_18920)	-	3919594..3919803 (-)	210	WP_060673776.1	winged helix-turn-helix domain-containing protein	-
A1R12_RS18925 (A1R12_18925)	htrA	3920293..3921489 (-)	1197	WP_022554034.1	S1C family serine protease	Regulator
A1R12_RS18930 (A1R12_18930)	vicX	3921576..3922370 (-)	795	WP_004393110.1	MBL fold metallo-hydrolase	Regulator
A1R12_RS18935 (A1R12_18935)	-	3922385..3923224 (-)	840	WP_014419340.1	two-component system regulatory protein YycI	-
A1R12_RS18940 (A1R12_18940)	yycH	3923211..3924569 (-)	1359	WP_014419341.1	two-component system activity regulator YycH	-
A1R12_RS18945 (A1R12_18945)	walK	3924559..3926394 (-)	1836	WP_004393106.1	cell wall metabolism sensor histidine kinase WalK	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 42589.43 Da
• Isoelectric Point: 8.2633

>NTDB_id=149745 A1R12_RS18925 WP_022554034.1 3920293..3921489(-) (htrA) [Bacillus amyloliquefaciens strain B15]
MDYNRDDEQYASEQPRRSKRGYFLSSLIGVIVGAALMAFLLPYWTGGDHGESSKSTSQRLGSEQVKTVNVNVNDAVTNMV
SRVSDSVVGVLNIQKTDIWGEGGEAGSGSGVIYKKNGNTSYIVTNHHVIAGATEIEISLKDGSRVPAELIGSDRLMDLAV
LKVKSDKIKSAAQFGNSDQVKVGEPVIAIGNPLGLEFAGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDAAINPGN
SGGALMDISGKVVGINSMKIAESAVEGIGLSIPSKLVIPVIQDLEKYGEVRRPFLGIEMKSLTDIASYHWSQTLKLPKGI
KTGAVIMGVDAFSPAGKAGLKKLDVITGFDGHKVNDVVDLRERLYRKKIGDRVNITFYRSGKKKTAEVKLTEADRLQK

Nucleotide

• Length: 1197 bp

>NTDB_id=149745 A1R12_RS18925 WP_022554034.1 3920293..3921489(-) (htrA) [Bacillus amyloliquefaciens strain B15]
GTGGATTATAATCGCGATGATGAACAGTACGCCTCCGAACAGCCCCGCCGCAGCAAGAGAGGGTACTTTCTATCAAGTCT
GATCGGCGTCATCGTCGGGGCCGCGCTCATGGCTTTCCTGCTGCCGTACTGGACAGGCGGAGACCATGGAGAAAGCAGCA
AAAGCACCAGCCAGCGTCTCGGCAGCGAACAGGTGAAAACAGTCAACGTCAATGTCAATGATGCTGTCACGAATATGGTC
AGCCGTGTATCAGATTCGGTAGTCGGTGTTCTCAATATCCAAAAGACCGATATTTGGGGAGAGGGCGGCGAAGCGGGAAG
CGGATCGGGCGTCATTTACAAAAAGAACGGAAACACTTCTTATATCGTAACCAATCACCATGTCATTGCAGGTGCGACTG
AAATTGAGATCAGCCTGAAGGATGGCTCACGCGTGCCTGCTGAGCTGATCGGGAGCGACCGTCTGATGGATCTCGCCGTG
CTGAAGGTGAAGTCTGATAAAATCAAATCGGCCGCCCAGTTCGGCAATTCTGATCAAGTCAAAGTCGGAGAACCGGTCAT
TGCGATCGGAAATCCGCTCGGGCTTGAATTTGCGGGATCAGTGACACAGGGGATCATTTCAGGCACGGAAAGGGCAGTGC
CCGTTGACTCAAACGGCGACGGACAGCCGGATTGGAATGCGGAAGTGCTGCAGACCGACGCCGCGATTAACCCCGGCAAC
AGCGGCGGCGCTTTGATGGATATATCGGGCAAGGTGGTCGGCATCAACTCAATGAAGATCGCTGAATCTGCCGTTGAAGG
CATCGGCCTGTCCATCCCGTCAAAGCTTGTCATTCCCGTTATTCAGGATTTAGAAAAATACGGAGAAGTCAGACGGCCTT
TCCTCGGTATTGAGATGAAATCCTTAACGGATATTGCGAGCTACCATTGGAGCCAGACGCTGAAACTTCCGAAAGGCATT
AAAACCGGGGCGGTCATTATGGGTGTCGACGCGTTTTCACCGGCCGGAAAAGCGGGTTTGAAAAAGCTCGACGTGATCAC
CGGGTTCGACGGACATAAGGTCAATGACGTTGTGGATCTCCGTGAGCGTCTGTATCGCAAAAAGATCGGCGACCGTGTGA
ACATCACGTTCTACCGTTCGGGAAAGAAAAAAACAGCGGAAGTCAAACTGACAGAAGCGGATCGATTACAGAAATAA

Domains

Predicted by InterProScan.

• Peptidase family M50 (Peptidase_M50) (248-394)

• Trypsin-like peptidase domain (Trypsin_2) (108-255)

• PDZ domain (PDZ_2) (293-390)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	43.182	99.497	0.43
htrA	Streptococcus mitis NCTC 12261	41.192	96.985	0.4
htrA	Streptococcus gordonii str. Challis substr. CH1	40.409	98.241	0.397