Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   AA974_RS00070 Genome accession   NZ_CP011487
Coordinates   11730..12473 (+) Length   247 a.a.
NCBI ID   WP_064432891.1    Uniprot ID   -
Organism   Helicobacter pylori strain PNG84A     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 6730..17473
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA974_RS00045 (AA974_00050) panD 8897..9247 (+) 351 WP_064432889.1 aspartate 1-decarboxylase -
  AA974_RS00050 (AA974_00055) - 9258..9551 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  AA974_RS00055 (AA974_00060) - 9551..10546 (+) 996 WP_064432890.1 PDZ domain-containing protein -
  AA974_RS00060 (AA974_00065) comB6 10552..11604 (+) 1053 WP_064434028.1 P-type conjugative transfer protein TrbL Machinery gene
  AA974_RS00065 (AA974_00070) comB7 11620..11733 (+) 114 WP_001217871.1 hypothetical protein Machinery gene
  AA974_RS00070 (AA974_00075) comB8 11730..12473 (+) 744 WP_064432891.1 type IV secretion system protein Machinery gene
  AA974_RS00075 (AA974_00080) comB9 12473..13432 (+) 960 WP_064432892.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  AA974_RS00080 (AA974_00085) comB10 13425..14561 (+) 1137 WP_064432893.1 DNA type IV secretion system protein ComB10 Machinery gene
  AA974_RS00085 (AA974_00090) - 14631..16049 (+) 1419 WP_064432894.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  AA974_RS00090 (AA974_00095) gmd 16059..17204 (+) 1146 WP_064432895.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28710.99 Da        Isoelectric Point: 8.9546

>NTDB_id=146292 AA974_RS00070 WP_064432891.1 11730..12473(+) (comB8) [Helicobacter pylori strain PNG84A]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKAQNSIY
TQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APINRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=146292 AA974_RS00070 WP_064432891.1 11730..12473(+) (comB8) [Helicobacter pylori strain PNG84A]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGACTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGCTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAGCGCAAAACAGCATTTAT
ACGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGCAGCTAAACTCATGAACGAAAACAAGTTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACTGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGATTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment