Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ASL18_RS10325 Genome accession   NZ_CP013959
Coordinates   2048210..2048833 (-) Length   207 a.a.
NCBI ID   WP_001045132.1    Uniprot ID   -
Organism   Staphylococcus aureus strain V605 isolate sequencing     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2043210..2053833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ASL18_RS10300 (ASL18_10305) - 2043705..2044901 (-) 1197 WP_000238227.1 exonuclease SbcCD subunit D -
  ASL18_RS10305 (ASL18_10310) - 2045192..2045290 (-) 99 WP_001791795.1 hypothetical protein -
  ASL18_RS10310 (ASL18_10315) - 2045674..2046018 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  ASL18_RS10315 (ASL18_10320) - 2046087..2047211 (-) 1125 WP_000992527.1 DUF445 domain-containing protein -
  ASL18_RS10320 (ASL18_10325) - 2047390..2047854 (-) 465 WP_000375864.1 helix-turn-helix transcriptional regulator -
  ASL18_RS10325 (ASL18_10330) vraR 2048210..2048833 (-) 624 WP_001045132.1 response regulator transcription factor Regulator
  ASL18_RS10330 (ASL18_10335) - 2048855..2049967 (-) 1113 WP_000437967.1 GAF domain-containing sensor histidine kinase -
  ASL18_RS10335 (ASL18_10340) - 2050130..2050951 (+) 822 WP_000669375.1 RluA family pseudouridine synthase -
  ASL18_RS10340 (ASL18_10345) fumC 2051414..2052799 (-) 1386 WP_000116224.1 class II fumarate hydratase -
  ASL18_RS10345 (ASL18_10350) - 2052995..2053390 (-) 396 WP_000901021.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23911.60 Da        Isoelectric Point: 5.5730

>NTDB_id=143689 ASL18_RS10325 WP_001045132.1 2048210..2048833(-) (vraR) [Staphylococcus aureus strain V605 isolate sequencing]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHLKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=143689 ASL18_RS10325 WP_001045132.1 2048210..2048833(-) (vraR) [Staphylococcus aureus strain V605 isolate sequencing]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCTTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATTGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-201)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.097

100

0.401
  degU Bacillus subtilis subsp. subtilis str. 168

34.685

100

0.372
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362