Detailed information NTG0141422

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: VN11_RS17165
• Genome accession: NZ_CP011010
• Coordinates: 3758420..3759793 (+)
• Length: 457 a.a.
• NCBI ID: WP_008265059.1
• Uniprot ID: B8L684
• Organism: Stenotrophomonas maltophilia strain ISMMS3 isolate Patient
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 3753420..3764793

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VN11_RS17150 (VN11_17175)	sucD	3754274..3755149 (-)	876	WP_005410793.1	succinate--CoA ligase subunit alpha	-
VN11_RS17155 (VN11_17180)	sucC	3755171..3756340 (-)	1170	WP_004154430.1	ADP-forming succinate--CoA ligase subunit beta	-
VN11_RS17160 (VN11_17185)	-	3756746..3758359 (+)	1614	WP_053450609.1	ATP-binding protein	-
VN11_RS17165 (VN11_17190)	pilR	3758420..3759793 (+)	1374	WP_008265059.1	sigma-54 dependent transcriptional regulator	Regulator
VN11_RS17170 (VN11_17195)	pilB	3759901..3761631 (-)	1731	WP_053450610.1	type IV-A pilus assembly ATPase PilB	Machinery gene
VN11_RS17175 (VN11_17200)	-	3761696..3763810 (-)	2115	WP_053450611.1	sulfatase-like hydrolase/transferase	-
VN11_RS17180 (VN11_17205)	pilA	3763913..3764329 (-)	417	WP_053450612.1	pilin	Machinery gene

Sequence

Protein

• Length: 457 a.a.
• Molecular weight: 49533.77 Da
• Isoelectric Point: 6.2014

>NTDB_id=141422 VN11_RS17165 WP_008265059.1 3758420..3759793(+) (pilR) [Stenotrophomonas maltophilia strain ISMMS3 isolate Patient]
MNETRSALVVDDERDIRELLVLTLGRMGLRISTAANLAEARELLASNPYDLCITDMRLPDGNGIELVSEIAQHYPRTPVA
MITAFGSMDLAVEALKAGAFDFVSKPVDISVLRGLVKHALELNNTERPAPGPSAEQGARLLGDSPAMDVLRTTIGKVARS
QAPVYILGESGVGKELVARTIHAQGARAAGPFVPVNCGAIPGELMESEFFGHRKGSFSGAHADKPGLFQAAHGGTLFLDE
VAELPLQMQVKLLRAIQEKSVRAVGAPNEEPVDVRILSATHRDLAELVEDGRFRHDLYYRINVIELKVPPLRERRQDLPE
LAAAVLARLARSHGRATPLLAPSALEALAQYAFPGNVRELENILERALALAEEDCIGADDLRLPQHAPRAPGSAAPAEAV
ADLQPGSAALPSYIEQLERSAIQRALEENRWNKTRTAAQLGITFRALRYKLKKLGME

Nucleotide

• Length: 1374 bp

>NTDB_id=141422 VN11_RS17165 WP_008265059.1 3758420..3759793(+) (pilR) [Stenotrophomonas maltophilia strain ISMMS3 isolate Patient]
ATGAACGAAACCCGCAGCGCCCTCGTCGTCGACGACGAACGCGACATCCGCGAACTGCTGGTGCTGACCCTCGGCCGCAT
GGGGCTGCGCATCAGTACCGCCGCCAACCTGGCCGAAGCACGTGAACTGCTGGCCAGCAATCCGTATGACCTGTGCATCA
CCGACATGCGCTTGCCGGATGGCAACGGCATCGAACTGGTCAGCGAGATCGCCCAGCACTATCCGCGCACGCCGGTGGCG
ATGATCACCGCCTTCGGCAGCATGGATCTGGCGGTGGAAGCGCTGAAGGCCGGTGCCTTCGACTTCGTCAGCAAGCCGGT
GGACATCTCGGTGCTGCGCGGCCTGGTCAAGCACGCACTGGAACTCAACAACACCGAACGCCCCGCGCCCGGCCCCAGTG
CCGAACAGGGCGCGCGCCTGCTTGGCGACTCGCCGGCCATGGACGTGCTGCGCACCACCATCGGCAAGGTCGCGCGCAGC
CAGGCGCCGGTGTACATCCTGGGCGAGTCCGGGGTGGGCAAGGAGCTGGTCGCGCGCACCATCCACGCCCAGGGTGCGCG
TGCGGCCGGCCCGTTCGTGCCGGTGAACTGCGGCGCCATCCCCGGCGAGCTGATGGAGAGTGAATTCTTCGGCCATCGCA
AGGGCAGCTTCAGCGGCGCGCACGCCGACAAGCCGGGCCTGTTCCAGGCCGCCCATGGCGGCACCCTGTTCCTGGACGAA
GTGGCCGAACTGCCGCTGCAGATGCAGGTGAAGCTGCTGCGCGCGATCCAGGAAAAATCGGTGCGTGCGGTTGGTGCGCC
CAACGAGGAACCGGTGGACGTGCGGATTCTCTCGGCCACCCACCGCGACCTGGCGGAACTGGTCGAGGACGGGCGCTTCC
GCCACGACCTGTACTACCGCATCAACGTGATCGAACTGAAGGTACCGCCGCTGCGTGAGCGCCGCCAGGACCTGCCGGAA
CTGGCTGCCGCGGTGCTGGCGCGGCTGGCCCGCAGCCATGGCCGCGCCACCCCGCTGCTGGCGCCGTCGGCACTGGAGGC
GCTGGCCCAGTACGCCTTCCCCGGCAATGTGCGCGAACTGGAGAACATCCTGGAACGTGCGCTGGCACTGGCCGAGGAAG
ACTGCATCGGTGCCGATGACCTGCGCCTGCCGCAGCACGCGCCGCGCGCGCCCGGCAGTGCCGCCCCCGCCGAAGCCGTG
GCCGACCTGCAGCCGGGCAGCGCCGCCCTGCCCTCCTACATCGAGCAGCTCGAGCGCAGCGCCATCCAGCGCGCGCTGGA
AGAGAACCGCTGGAACAAGACCCGCACCGCCGCGCAGCTGGGCATCACCTTCCGTGCGCTGCGCTACAAGCTGAAGAAGC
TGGGAATGGAGTAG

Domains

Predicted by InterproScan.

• Bacterial regulatory protein, Fis family (HTH_8) (414-454)

• Response regulator receiver domain (Response_reg) (8-115)

• Sigma-54 interaction domain (Sigma54_activat) (141-306)

3D structure

• AlphaFold DB: B8L684

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	63.158	99.781	0.63
pilR	Acinetobacter baumannii strain A118	48.164	100	0.488