Detailed information NTG0141353

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: UP12_RS16590
• Genome accession: NZ_CP011007
• Coordinates: 3263142..3264317 (-)
• Length: 391 a.a.
• NCBI ID: WP_024719243.1
• Uniprot ID: A0A081LEM4
• Organism: Bacillus pumilus strain SH-B9
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3258142..3269317

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UP12_RS16560 (UP12_16575)	-	3258310..3258729 (-)	420	WP_034660147.1	TIGR03826 family flagellar region protein	-
UP12_RS20320 (UP12_16580)	comFC	3258786..3259472 (-)	687	WP_208856849.1	ComF family protein	Machinery gene
UP12_RS16570 (UP12_16585)	-	3259469..3259762 (-)	294	WP_061409760.1	competence protein ComFB	-
UP12_RS16575 (UP12_16590)	comFA	3259829..3261208 (-)	1380	WP_151282355.1	DEAD/DEAH box helicase	Machinery gene
UP12_RS16580 (UP12_16595)	-	3261328..3262170 (-)	843	WP_058013557.1	DegV family protein	-
UP12_RS16585 (UP12_16600)	degU	3262388..3263077 (-)	690	WP_008348273.1	two-component system response regulator DegU	Regulator
UP12_RS16590 (UP12_16605)	degS	3263142..3264317 (-)	1176	WP_024719243.1	sensor histidine kinase	Regulator
UP12_RS16595 (UP12_16610)	-	3264539..3265207 (+)	669	WP_058013556.1	YigZ family protein	-
UP12_RS16600 (UP12_16615)	-	3265192..3266247 (+)	1056	WP_061409762.1	LCP family protein	-
UP12_RS16605 (UP12_16620)	-	3266283..3267350 (-)	1068	WP_058013554.1	MraY family glycosyltransferase	-
UP12_RS16610 (UP12_16625)	-	3267482..3268672 (-)	1191	WP_058013890.1	glycosyltransferase	-

Sequence

Protein

• Length: 391 a.a.
• Molecular weight: 45550.27 Da
• Isoelectric Point: 5.8757

>NTDB_id=141353 UP12_RS16590 WP_024719243.1 3263142..3264317(-) (degS) [Bacillus pumilus strain SH-B9]
MTTPKMDPKLLDSIIMKMLSTVDGSKDEVFRIGEQSRQQYESLVEELKQIKQQVNEVIDFGDKLEVHTRHARNRLSEVSR
NFNKFSEEEIREAYEKAHNLQVELTMIQQREKQLRERRDDLERRLLSLQDVIERSETLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEEGFKEIRSLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEEYDGKTKITFQCLGDTENERIASQFEVALFRLAQEAVTNSLKHSEAEEISVKVEV
TKDFVTLIIKDDGKGFDMKDVKTNKNKSFGLLGMKERVDLLEGKMTIDSKIGLGTFIMIRVPLTLQNKIVK

Nucleotide

• Length: 1176 bp

>NTDB_id=141353 UP12_RS16590 WP_024719243.1 3263142..3264317(-) (degS) [Bacillus pumilus strain SH-B9]
ATGACAACACCTAAAATGGATCCGAAATTATTGGATTCAATCATCATGAAAATGCTAAGTACAGTTGATGGCAGCAAGGA
CGAAGTATTTAGGATAGGCGAACAGTCCCGTCAACAATATGAAAGCCTTGTAGAAGAGCTGAAGCAAATCAAACAGCAAG
TAAACGAAGTAATTGATTTTGGGGATAAACTAGAAGTCCATACGAGACATGCTAGAAATCGTTTATCTGAGGTCAGCAGA
AACTTCAACAAATTTAGCGAAGAAGAAATACGGGAGGCCTACGAAAAAGCACATAATCTGCAAGTGGAACTCACCATGAT
CCAGCAGCGCGAAAAGCAGCTGAGAGAAAGAAGAGACGATCTGGAAAGACGATTGTTAAGCCTGCAAGACGTCATTGAAC
GCTCTGAAACGCTTGTGAGCCAGATCACAGTGGTTCTCAACTATCTCAACCAGGACTTACGCCAAGTTGGCGTGTTACTT
GAAGATGCTCAAGCAAAACAAGATTTTGGACTTAGAATTATTGAAGCCCAAGAAGAAGAACGTAAAAGGGTATCCCGTGA
AATTCATGACGGTCCCGCCCAGATGCTGGCAAACGTGATGATGCGTTCTGAATTAATTGAACGGATTTTCAGAGATCGTG
GGACAGAAGAAGGCTTTAAAGAAATTAGAAGTCTCAGACAGAATGTGCGAAATGCTCTGTACGAAGTGAGAAGAATCATT
TATGATTTAAGACCAATGGCTTTAGATGATTTGGGTCTCATTCCGACGCTAAGAAAATATTTAAACACAATCGAAGAGTA
TGATGGAAAAACCAAGATCACGTTCCAATGCCTAGGGGATACAGAAAATGAAAGAATTGCTTCTCAATTCGAAGTGGCAC
TGTTTAGACTAGCCCAAGAAGCTGTCACAAATTCATTGAAGCATTCCGAAGCTGAAGAAATCTCTGTAAAAGTAGAAGTG
ACGAAAGACTTTGTCACGTTAATTATCAAAGACGATGGAAAAGGCTTTGATATGAAAGATGTGAAAACAAACAAAAACAA
ATCCTTCGGTTTACTTGGCATGAAAGAACGCGTAGACTTACTTGAAGGTAAAATGACCATAGACTCAAAAATAGGTCTAG
GGACATTCATCATGATTCGCGTGCCATTAACATTGCAAAATAAAATTGTAAAATAG

Domains

Predicted by InterproScan.

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A0A081LEM4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	85.455	98.465	0.841