Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CUGBS08_RS07895 Genome accession   NZ_CP010874
Coordinates   1545865..1546554 (-) Length   229 a.a.
NCBI ID   WP_000516681.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain CU_GBS_08     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1540865..1551554
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CUGBS08_RS07875 (CUGBS08_01585) dnaI 1541668..1542570 (-) 903 WP_000843629.1 primosomal protein DnaI -
  CUGBS08_RS07880 (CUGBS08_01586) - 1542567..1543742 (-) 1176 WP_000074512.1 DnaD domain protein -
  CUGBS08_RS07885 (CUGBS08_01587) nrdR 1543742..1544221 (-) 480 WP_001203682.1 transcriptional regulator NrdR -
  CUGBS08_RS07890 (CUGBS08_01588) - 1544370..1545875 (-) 1506 WP_000791116.1 HAMP domain-containing sensor histidine kinase -
  CUGBS08_RS07895 (CUGBS08_01589) covR 1545865..1546554 (-) 690 WP_000516681.1 response regulator transcription factor Regulator
  CUGBS08_RS07900 (CUGBS08_01590) - 1546789..1547322 (-) 534 WP_000927543.1 YceD family protein -
  CUGBS08_RS07905 (CUGBS08_01591) htpX 1547427..1548317 (-) 891 WP_000966819.1 zinc metalloprotease HtpX -
  CUGBS08_RS07910 (CUGBS08_01592) - 1548338..1548892 (-) 555 WP_000537055.1 LemA family protein -
  CUGBS08_RS07915 (CUGBS08_01593) rsmG 1549020..1549733 (+) 714 WP_000188792.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  CUGBS08_RS07920 (CUGBS08_01594) - 1549748..1551127 (+) 1380 WP_000680109.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26547.55 Da        Isoelectric Point: 4.8094

>NTDB_id=140468 CUGBS08_RS07895 WP_000516681.1 1545865..1546554(-) (covR) [Streptococcus agalactiae strain CU_GBS_08]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=140468 CUGBS08_RS07895 WP_000516681.1 1545865..1546554(-) (covR) [Streptococcus agalactiae strain CU_GBS_08]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGTGGTA
GTTTCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.476

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

45.887

100

0.463
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment