Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ACT75_RS05440 Genome accession   NZ_CP012959
Coordinates   1130594..1131214 (+) Length   206 a.a.
NCBI ID   WP_196755642.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain 624     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1125594..1136214
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACT75_RS05400 (ACT75_05395) mutM 1125629..1126444 (-) 816 WP_005554465.1 bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase -
  ACT75_RS05405 (ACT75_05400) rpmG 1126526..1126696 (-) 171 WP_005542835.1 50S ribosomal protein L33 -
  ACT75_RS05410 (ACT75_05405) rpmB 1126708..1126944 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  ACT75_RS05415 (ACT75_05410) radC 1127131..1127790 (-) 660 WP_005549324.1 RadC family protein Machinery gene
  ACT75_RS05420 (ACT75_05415) coaBC 1127968..1129167 (+) 1200 WP_005540229.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  ACT75_RS05425 (ACT75_05420) dut 1129236..1129691 (+) 456 WP_005540230.1 dUTP diphosphatase -
  ACT75_RS05430 (ACT75_05425) slmA 1129691..1130290 (+) 600 WP_005540234.1 nucleoid occlusion factor SlmA -
  ACT75_RS05435 (ACT75_05430) - 1130314..1130532 (+) 219 WP_005540236.1 YheU family protein -
  ACT75_RS05440 (ACT75_05435) crp 1130594..1131214 (+) 621 WP_196755642.1 cAMP-activated global transcriptional regulator CRP Regulator
  ACT75_RS05445 (ACT75_05440) gorA 1131347..1132717 (-) 1371 WP_005540240.1 glutathione-disulfide reductase -
  ACT75_RS05450 (ACT75_05445) - 1132812..1133657 (-) 846 WP_005540242.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23360.99 Da        Isoelectric Point: 7.8328

>NTDB_id=137730 ACT75_RS05440 WP_196755642.1 1130594..1131214(+) (crp) [Aggregatibacter actinomycetemcomitans strain 624]
MQSMDPTLEWFLSHCHIHKYPSKSTLINAGEKAETLYYLIQGSVSVLVKDEDGKEMILTYLSQGDFFGEAGLFEEGQRRS
AWIKAKSSCEVAEISYRKFRQLIQVNPEILMYLTAQLAYRLQNTSRQVSNLAFLDVTGRIAQTLLNLAKMPEAMTHPDGM
QIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide


Download         Length: 621 bp        

>NTDB_id=137730 ACT75_RS05440 WP_196755642.1 1130594..1131214(+) (crp) [Aggregatibacter actinomycetemcomitans strain 624]
ATGCAATCAATGGATCCGACACTTGAGTGGTTTTTATCCCACTGCCATATCCATAAATATCCGTCTAAAAGCACATTAAT
CAACGCCGGCGAAAAAGCCGAGACACTTTATTATTTAATTCAAGGCTCCGTGTCCGTTTTGGTCAAAGATGAAGACGGCA
AAGAAATGATCCTCACCTACTTAAGCCAAGGGGATTTTTTCGGCGAAGCGGGCTTATTTGAAGAAGGACAACGTCGTTCT
GCGTGGATTAAAGCAAAATCCTCCTGTGAAGTGGCGGAAATTTCTTATCGTAAATTTCGCCAGCTGATTCAAGTCAACCC
TGAAATTCTGATGTATCTTACGGCCCAGTTAGCGTATCGGTTACAAAACACTTCGCGCCAAGTAAGTAATTTAGCCTTTT
TAGATGTCACCGGTCGCATCGCGCAAACCTTGCTCAATCTGGCAAAAATGCCGGAAGCGATGACTCACCCGGACGGTATG
CAAATTAAAATCACCCGCCAGGAAATCGGACAAATGGTCGGTTGTTCGCGGGAAACCGTCGGGCGTATTCTGAAAATGCT
GGAAGATCAACACCTCATCTCGGCACACGGCAAAACCATCGTAGTTTACGGCACCCGCTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(19-105)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(138-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

82.178

98.058

0.806
  crp Haemophilus influenzae Rd KW20

80.693

98.058

0.791
  crp Acinetobacter baumannii D1279779

47.236

96.602

0.456

Multiple sequence alignment