Detailed information NTG0136369

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: GBS85147_RS03820
• Genome accession: NZ_CP010319
• Coordinates: 727422..729659 (+)
• Length: 745 a.a.
• NCBI ID: WP_000939914.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain GBS85147
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 722422..734659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GBS85147_RS03795 (GBS85147_0769)	-	723017..724603 (+)	1587	WP_000673086.1	DEAD/DEAH box helicase	-
GBS85147_RS03800 (GBS85147_0770)	-	724788..725054 (-)	267	WP_000598736.1	GIY-YIG nuclease family protein	-
GBS85147_RS03805 (GBS85147_0771)	-	725047..725811 (-)	765	WP_000567424.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
GBS85147_RS03810 (GBS85147_0772)	-	725946..726686 (+)	741	WP_000500221.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
GBS85147_RS03815 (GBS85147_0773)	-	726785..727438 (+)	654	WP_000461740.1	helix-hairpin-helix domain-containing protein	-
GBS85147_RS03820 (GBS85147_0774)	comEC/celB	727422..729659 (+)	2238	WP_000939914.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GBS85147_RS03825 (GBS85147_0775)	-	729784..730593 (+)	810	WP_000153216.1	Cof-type HAD-IIB family hydrolase	-
GBS85147_RS03830 (GBS85147_0776)	-	730604..731548 (+)	945	WP_000200826.1	LacI family DNA-binding transcriptional regulator	-
GBS85147_RS03835 (GBS85147_0777)	-	731607..732599 (-)	993	WP_000800991.1	alpha/beta hydrolase fold domain-containing protein	-
GBS85147_RS03840 (GBS85147_0778)	-	732775..733503 (+)	729	WP_053039134.1	bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG	-
GBS85147_RS03845 (GBS85147_0779)	holA	733557..734594 (+)	1038	WP_000560292.1	DNA polymerase III subunit delta	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85398.25 Da
• Isoelectric Point: 9.7775

>NTDB_id=136369 GBS85147_RS03820 WP_000939914.1 727422..729659(+) (comEC/celB) [Streptococcus agalactiae strain GBS85147]
MLQLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFTFIFLIYQYDRETIFKTIAIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIEVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLSQHRSFFALMSKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDNMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPIVKLGCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRLRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDDLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKRLSKIGVAVKSIEAGDKLAVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=136369 GBS85147_RS03820 WP_000939914.1 727422..729659(+) (comEC/celB) [Streptococcus agalactiae strain GBS85147]
ATGTTACAATTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTACTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAGCAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTGAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTACACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATCATTGCAGATATCAAACTCGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATCTCAACATAGGTCTTTCTT
TGCTCTTATGTCTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GACTTTTGTTTGGATATCTAGATAAGACCTTTGATAACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCTCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCGCCTATCGTTAAATTAGGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTGTTATTAAAATGGAC
TGGGCAACTGTTTCCAAGGCCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTCGCGATTTTAGATGTTGGACAAGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGTTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAATCAGTCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGCATTAGCAAGATAGATGATTTAGTGATAACTCACACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCGTTTATCAAAGATAGGTGTAGCGGTAAAATCTATAGAAGCCGGTGATAAACTTGCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTGTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

• Domain of unknown function (DUF4131) (DUF4131) (28-177)

• Competence protein (Competence) (215-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.602	100	0.49
comEC/celB	Streptococcus mitis NCTC 12261	48.4	100	0.487
comEC/celB	Streptococcus pneumoniae TIGR4	47.137	100	0.475
comEC/celB	Streptococcus pneumoniae Rx1	46.667	100	0.47
comEC/celB	Streptococcus pneumoniae D39	46.667	100	0.47
comEC/celB	Streptococcus pneumoniae R6	46.667	100	0.47
comEC	Lactococcus lactis subsp. cremoris KW2	44.145	99.732	0.44