Detailed information NTG0133721

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: QI18_RS08875
• Genome accession: NZ_CP010050
• Coordinates: 1803106..1804095 (-)
• Length: 329 a.a.
• NCBI ID: WP_012898311.1
• Uniprot ID: A0A0A7T187
• Organism: Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1798106..1809095

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QI18_RS08860 (QI18_08860)	-	1799472..1800398 (-)	927	WP_010906107.1	peptidyl-prolyl cis-trans isomerase	-
QI18_RS08865 (QI18_08865)	-	1800552..1801235 (-)	684	WP_010906108.1	O-methyltransferase	-
QI18_RS08870 (QI18_08870)	pepF	1801238..1803043 (-)	1806	WP_039115799.1	oligoendopeptidase F	Regulator
QI18_RS08875 (QI18_08875)	coiA	1803106..1804095 (-)	990	WP_012898311.1	competence protein CoiA	Machinery gene
QI18_RS08880 (QI18_08880)	-	1804169..1805254 (-)	1086	WP_012898312.1	YdcF family protein	-
QI18_RS08885 (QI18_08885)	-	1805416..1806264 (-)	849	WP_010906111.1	alpha/beta hydrolase	-
QI18_RS08890 (QI18_08890)	-	1806456..1807877 (-)	1422	WP_039115802.1	NCS2 family permease	-
QI18_RS08895 (QI18_08895)	-	1808184..1809020 (+)	837	WP_003130402.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 39384.91 Da
• Isoelectric Point: 8.5207

>NTDB_id=133721 QI18_RS08875 WP_012898311.1 1803106..1804095(-) (coiA) [Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk]
MLTAIDENGQVVNLLEIEVKELTGKYFCPSCKSELFIKNGEIKMTHFAHKSLKACDLWLENESEQHLGLKKALYQWFKKT
DKVEIEAYIPEFKQRPDLLVNDKIAIEIQCSHLSTKRLKERTENYQVHGFTVLWLMGQDLWLKEQITELQKNLVYFSENR
GFYYWELDFKAQKMRLKSLIHEDLRGKIIYLQEEIPFGEGRLIEQLRLPFLSQKLLTIPLIVDLKLAEFIRQQLYYCSPK
WLKLQEKYYQRGENLLNLTFERSFIAPLGLNLLEVFDDKIPLHKFTQIKQNINLYYENFLINFQQNSFKAVYPPRFYAIM
KKQKKDMNE

Nucleotide

• Length: 990 bp

>NTDB_id=133721 QI18_RS08875 WP_012898311.1 1803106..1804095(-) (coiA) [Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk]
ATGTTGACAGCAATTGATGAAAATGGACAAGTAGTAAACTTATTAGAAATAGAAGTAAAAGAACTGACAGGAAAATATTT
TTGTCCTTCTTGTAAATCAGAGTTATTTATAAAAAATGGTGAAATAAAGATGACTCACTTTGCTCATAAATCTCTCAAAG
CTTGCGACTTATGGCTTGAAAACGAATCTGAACAACATTTAGGATTAAAAAAAGCACTCTATCAATGGTTTAAAAAAACT
GATAAGGTGGAAATTGAAGCTTATATTCCTGAATTTAAGCAGAGGCCAGATTTATTGGTAAATGATAAAATAGCTATTGA
AATTCAATGTTCTCATCTTTCTACGAAACGTTTAAAAGAAAGGACAGAGAATTATCAAGTCCACGGTTTTACGGTACTTT
GGCTTATGGGGCAAGATTTATGGTTAAAAGAGCAAATAACAGAACTTCAAAAAAATCTAGTCTATTTTTCAGAAAATAGA
GGTTTCTATTATTGGGAGTTAGATTTCAAAGCTCAGAAGATGAGATTAAAATCCCTGATTCATGAAGATTTGCGTGGAAA
AATTATTTATTTACAAGAAGAAATTCCTTTTGGGGAAGGACGACTTATTGAGCAATTACGACTGCCTTTTTTATCACAAA
AGTTACTGACAATACCACTTATTGTTGATCTTAAACTAGCAGAATTTATTCGTCAGCAACTTTATTATTGTTCACCAAAA
TGGTTGAAACTTCAGGAAAAATATTACCAAAGAGGTGAAAATTTGTTGAATTTGACTTTTGAACGTTCATTTATTGCGCC
TTTGGGATTGAACTTACTTGAAGTTTTTGATGATAAAATTCCTTTACATAAATTTACTCAAATTAAGCAGAATATTAATC
TTTATTATGAAAACTTTTTAATAAATTTTCAGCAAAATAGCTTTAAGGCAGTCTATCCTCCCCGTTTCTATGCTATAATG
AAAAAGCAGAAGAAGGATATGAATGAATGA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (1-266)

3D structure

• AlphaFold DB: A0A0A7T187

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Lactococcus lactis subsp. cremoris KW2	75.767	99.088	0.751
coiA	Streptococcus pneumoniae TIGR4	44.41	97.872	0.435
coiA	Streptococcus pneumoniae Rx1	44.41	97.872	0.435
coiA	Streptococcus pneumoniae D39	44.41	97.872	0.435
coiA	Streptococcus pneumoniae R6	44.41	97.872	0.435
coiA	Streptococcus mitis NCTC 12261	44.41	97.872	0.435