Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   LA24_RS00630 Genome accession   NZ_CP009419
Coordinates   134251..134715 (-) Length   154 a.a.
NCBI ID   WP_162818945.1    Uniprot ID   -
Organism   Neisseria meningitidis M7124     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 128340..140932 134251..134715 within 0


Gene organization within MGE regions


Location: 128340..140932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA24_RS00595 (LA24_00620) - 128340..129986 (-) 1647 WP_002214929.1 TIGR02391 family protein -
  LA24_RS00600 (LA24_00625) - 130000..131055 (-) 1056 WP_002221681.1 DNA cytosine methyltransferase -
  LA24_RS13355 (LA24_00640) - 131461..131586 (-) 126 Protein_111 IS5/IS1182 family transposase -
  LA24_RS00615 (LA24_00645) - 131676..132641 (+) 966 WP_002216744.1 IS30-like element IS1655 family transposase -
  LA24_RS11470 - 132667..133017 (-) 351 Protein_113 IS5/IS1182 family transposase -
  LA24_RS14810 (LA24_00655) - 133356..133624 (+) 269 Protein_114 5'-nucleotidase -
  LA24_RS00625 (LA24_00660) comP 133714..134163 (-) 450 WP_002221685.1 type IV pilin protein Machinery gene
  LA24_RS00630 (LA24_00665) comE 134251..134715 (-) 465 WP_162818945.1 helix-hairpin-helix domain-containing protein Machinery gene
  LA24_RS00665 (LA24_00700) dksA 140516..140932 (-) 417 WP_002215267.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16459.71 Da        Isoelectric Point: 10.9585

>NTDB_id=129027 LA24_RS00630 WP_162818945.1 134251..134715(-) (comE) [Neisseria meningitidis M7124]
MLCPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPAIPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=129027 LA24_RS00630 WP_162818945.1 134251..134715(-) (comE) [Neisseria meningitidis M7124]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTATACCGGCCGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734

Multiple sequence alignment