Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   LA24_RS00625 Genome accession   NZ_CP009419
Coordinates   133714..134163 (-) Length   149 a.a.
NCBI ID   WP_002221685.1    Uniprot ID   A1KW94
Organism   Neisseria meningitidis M7124     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 128340..140932 133714..134163 within 0
IScluster/Tn 131676..133017 133714..134163 flank 697


Gene organization within MGE regions


Location: 128340..140932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA24_RS00595 (LA24_00620) - 128340..129986 (-) 1647 WP_002214929.1 TIGR02391 family protein -
  LA24_RS00600 (LA24_00625) - 130000..131055 (-) 1056 WP_002221681.1 DNA cytosine methyltransferase -
  LA24_RS13355 (LA24_00640) - 131461..131586 (-) 126 Protein_111 IS5/IS1182 family transposase -
  LA24_RS00615 (LA24_00645) - 131676..132641 (+) 966 WP_002216744.1 IS30-like element IS1655 family transposase -
  LA24_RS11470 - 132667..133017 (-) 351 Protein_113 IS5/IS1182 family transposase -
  LA24_RS14810 (LA24_00655) - 133356..133624 (+) 269 Protein_114 5'-nucleotidase -
  LA24_RS00625 (LA24_00660) comP 133714..134163 (-) 450 WP_002221685.1 type IV pilin protein Machinery gene
  LA24_RS00630 (LA24_00665) comE 134251..134715 (-) 465 WP_162818945.1 helix-hairpin-helix domain-containing protein Machinery gene
  LA24_RS00665 (LA24_00700) dksA 140516..140932 (-) 417 WP_002215267.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16848.83 Da        Isoelectric Point: 9.7951

>NTDB_id=129026 LA24_RS00625 WP_002221685.1 133714..134163(-) (comP) [Neisseria meningitidis M7124]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYIEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=129026 LA24_RS00625 WP_002221685.1 133714..134163(-) (comP) [Neisseria meningitidis M7124]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATATTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1KW94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

99.329

100

0.993
  comP Neisseria meningitidis 8013

98.658

100

0.987
  comP Neisseria subflava NJ9703

48.98

98.658

0.483

Multiple sequence alignment