Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   SpyM6D471_RS06420 Genome accession   NZ_CP011415
Coordinates   1271931..1272596 (-) Length   221 a.a.
NCBI ID   WP_002983685.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain D471     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1266931..1277596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SpyM6D471_RS06415 (SpyM6D471_06410) hpf 1271303..1271851 (-) 549 WP_002988974.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SpyM6D471_RS06420 (SpyM6D471_06415) comFC/cflB 1271931..1272596 (-) 666 WP_002983685.1 ComF family protein Machinery gene
  SpyM6D471_RS06425 (SpyM6D471_06420) comFA/cflA 1272568..1273893 (-) 1326 WP_011184811.1 DEAD/DEAH box helicase Machinery gene
  SpyM6D471_RS06430 (SpyM6D471_06425) - 1273949..1274581 (+) 633 WP_009880468.1 YigZ family protein -
  SpyM6D471_RS06435 (SpyM6D471_06430) cysK 1274709..1275650 (+) 942 WP_011184813.1 cysteine synthase A -
  SpyM6D471_RS06440 (SpyM6D471_06435) - 1275668..1276045 (-) 378 WP_002991882.1 S1 RNA-binding domain-containing protein -
  SpyM6D471_RS06445 (SpyM6D471_06440) - 1276045..1277445 (-) 1401 WP_011888672.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25163.41 Da        Isoelectric Point: 9.4626

>NTDB_id=128038 SpyM6D471_RS06420 WP_002983685.1 1271931..1272596(-) (comFC/cflB) [Streptococcus pyogenes strain D471]
MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSVCATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNA
AMKAYFSQYKFQGDYLLRKVFAVELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLSIAR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=128038 SpyM6D471_RS06420 WP_002983685.1 1271931..1272596(-) (comFC/cflB) [Streptococcus pyogenes strain D471]
ATGATCTGTCTACTATGTCAACAAATTAGTCAAACACCAATAAGTATTACAGAAATCATCTTTTTAAGGCGTATCTCTTC
ACCGATTTGTCAACAATGTCAAAAAAGCTTTCAAAAGATAGGAAAAAGTGTTTGTGCGACATGTTGTGCAAACTCAGATA
TAATAGCTTGTCGAGATTGTCTAAAATGGGAAAACAAAGGATACAATGTAAATCATAGAAGCTTATATTGTTATAATGCT
GCTATGAAAGCATACTTCAGTCAATATAAGTTTCAAGGAGACTATTTATTAAGGAAAGTTTTTGCAGTAGAACTTGCCGA
TGTTATTACCAAGTACTATAAAGGCTATATTCCAGTCCCGGTTCCTGTAAGTCCCGGTTGTTTTCGAGAAAGACAATTTA
ATCAAGTGAGCGCTATTCTTGAGGCAGCTAATGTTAGCTACCTTTCTCTTTTTGAAAAGCTAGATAATACTCACCAATCT
TCCAGAACAAAAAAAGAGAGATTATTAGTAGAAAAATCTTATCGACTACTAAAAGTATCAAACATTCCTGATAAAATCCT
TATAGTAGATGATATTTATACTACTGGTAGTACAATTATCGCTCTTAGAAAACAATTGGCTAAAGTAGCAAATAGTGACA
TTAAAAGTTTGTCAATTGCACGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae D39

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae R6

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae TIGR4

41.629

100

0.416
  comFC/cflB Streptococcus mitis SK321

41.629

100

0.416
  comFC/cflB Streptococcus mitis NCTC 12261

41.176

100

0.412

Multiple sequence alignment