Detailed information NTG0126840

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: ID12_RS02245
• Genome accession: NZ_CP009108
• Coordinates: 441218..442393 (-)
• Length: 391 a.a.
• NCBI ID: WP_024719243.1
• Uniprot ID: A0A081LEM4
• Organism: Bacillus altitudinis strain GR-8
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 436218..447393

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ID12_RS02215 (ID12_02290)	-	436404..436823 (-)	420	WP_017357864.1	TIGR03826 family flagellar region protein	-
ID12_RS02220 (ID12_02295)	comFC	436880..437461 (-)	582	WP_234717161.1	ComF family protein	Machinery gene
ID12_RS02225 (ID12_02300)	-	437563..437856 (-)	294	WP_035701582.1	late competence development ComFB family protein	-
ID12_RS02230 (ID12_02305)	comFA	437921..439300 (-)	1380	WP_142675479.1	DEAD/DEAH box helicase	Machinery gene
ID12_RS02235 (ID12_02310)	-	439420..440262 (-)	843	WP_024719242.1	DegV family protein	-
ID12_RS02240 (ID12_02315)	degU	440464..441153 (-)	690	WP_008348273.1	two-component system response regulator DegU	Regulator
ID12_RS02245 (ID12_02320)	degS	441218..442393 (-)	1176	WP_024719243.1	sensor histidine kinase	Regulator
ID12_RS02250 (ID12_02325)	-	442615..443283 (+)	669	WP_050826655.1	YigZ family protein	-
ID12_RS02255 (ID12_02330)	-	443268..444365 (+)	1098	WP_007499958.1	LCP family protein	-
ID12_RS02260 (ID12_02335)	-	444403..445470 (-)	1068	WP_007499956.1	glycosyltransferase family 4 protein	-
ID12_RS02265 (ID12_02340)	tuaH	445605..446852 (-)	1248	WP_050826656.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 391 a.a.
• Molecular weight: 45550.27 Da
• Isoelectric Point: 5.8757

>NTDB_id=126840 ID12_RS02245 WP_024719243.1 441218..442393(-) (degS) [Bacillus altitudinis strain GR-8]
MTTPKMDPKLLDSIIMKMLSTVDGSKDEVFRIGEQSRQQYESLVEELKQIKQQVNEVIDFGDKLEVHTRHARNRLSEVSR
NFNKFSEEEIREAYEKAHNLQVELTMIQQREKQLRERRDDLERRLLSLQDVIERSETLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEEGFKEIRSLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEEYDGKTKITFQCLGDTENERIASQFEVALFRLAQEAVTNSLKHSEAEEISVKVEV
TKDFVTLIIKDDGKGFDMKDVKTNKNKSFGLLGMKERVDLLEGKMTIDSKIGLGTFIMIRVPLTLQNKIVK

Nucleotide

• Length: 1176 bp

>NTDB_id=126840 ID12_RS02245 WP_024719243.1 441218..442393(-) (degS) [Bacillus altitudinis strain GR-8]
ATGACAACACCTAAAATGGATCCGAAGTTATTGGATTCAATCATCATGAAAATGCTAAGTACAGTTGATGGCAGTAAGGA
CGAAGTATTTAGAATCGGCGAACAGTCCCGTCAACAATATGAAAGCCTAGTAGAAGAGCTCAAGCAAATTAAACAGCAAG
TCAACGAAGTAATTGATTTTGGGGATAAACTAGAAGTACATACGAGACATGCTAGAAATCGATTATCTGAGGTCAGCAGA
AACTTCAACAAATTCAGCGAAGAAGAAATACGAGAAGCCTATGAAAAAGCACATAACCTGCAAGTAGAATTGACCATGAT
CCAGCAGCGCGAAAAACAGCTGAGGGAAAGAAGAGATGATCTCGAAAGACGATTGTTAAGCTTACAAGATGTCATTGAAC
GTTCAGAAACGCTTGTGAGCCAGATCACGGTCGTTCTCAACTACTTGAACCAAGATTTACGTCAGGTCGGTGTTTTACTT
GAAGATGCTCAGGCAAAACAAGATTTTGGACTAAGAATTATTGAAGCCCAGGAAGAAGAGCGCAAAAGGGTATCACGAGA
AATCCATGATGGACCTGCTCAGATGCTGGCAAACGTGATGATGCGTTCAGAACTAATTGAACGAATTTTTAGAGACCGTG
GAACAGAAGAAGGCTTTAAAGAAATTAGAAGTCTAAGACAGAATGTGCGAAATGCACTGTACGAAGTGAGAAGAATCATT
TATGATTTAAGACCGATGGCTTTAGATGATTTGGGTCTCATTCCGACACTGCGAAAATACTTAAACACAATTGAAGAATA
TGATGGAAAAACCAAAATTACGTTCCAATGCCTAGGGGATACAGAAAATGAAAGAATTGCTTCTCAGTTCGAAGTGGCAC
TGTTTAGACTAGCCCAAGAAGCTGTCACAAATTCATTGAAGCATTCCGAAGCTGAAGAAATCTCTGTAAAAGTAGAAGTG
ACAAAAGACTTTGTCACGTTAATTATCAAAGACGATGGAAAAGGCTTTGATATGAAAGATGTGAAAACAAATAAAAACAA
ATCCTTTGGGTTACTTGGTATGAAAGAGCGCGTAGACTTACTAGAAGGTAAAATGACCATAGACTCAAAAATAGGTCTAG
GGACATTCATCATGATTAGAGTACCGTTAACATTACAAAATAAAATTGTAAAATAG

Domains

Predicted by InterproScan.

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A0A081LEM4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	85.455	98.465	0.841