Detailed information NTG0124796

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: RDF_RS01110
• Genome accession: NZ_CP010867
• Coordinates: 189925..190386 (+)
• Length: 153 a.a.
• NCBI ID: WP_001878820.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SS1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 184925..195386

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDF_RS01080 (RDF_0164)	-	186540..186905 (+)	366	WP_000285373.1	DUF1033 family protein	-
RDF_RS01085 (RDF_0165)	comGA	187078..188049 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
RDF_RS01090 (RDF_0166)	comGB	187943..188986 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
RDF_RS01095 (RDF_0167)	comGC/cglC	188983..189312 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
RDF_RS01100 (RDF_0168)	comGD	189287..189700 (+)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
RDF_RS01105 (RDF_0169)	comGE	189672..189971 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
RDF_RS01110 (RDF_0170)	comGF	189925..190386 (+)	462	WP_001878820.1	competence type IV pilus minor pilin ComGF	Machinery gene
RDF_RS01115 (RDF_0171)	comGG	190364..190735 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
RDF_RS01120 (RDF_0172)	comGH	190850..191824 (+)	975	WP_001008574.1	class I SAM-dependent methyltransferase	Machinery gene
RDF_RS01125 (RDF_0173)	-	191856..193049 (+)	1194	WP_000047534.1	acetate kinase	-
RDF_RS01130 (RDF_0174)	-	193201..193407 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
RDF_RS11260 (RDF_0175)	-	193466..193603 (+)	138	WP_001865900.1	hypothetical protein	-
RDF_RS01135 (RDF_0176)	-	193644..194099 (+)	456	WP_000905673.1	hypothetical protein	-
RDF_RS01140 (RDF_0177)	-	194168..194833 (+)	666	WP_000008113.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17874.95 Da
• Isoelectric Point: 10.0299

>NTDB_id=124796 RDF_RS01110 WP_001878820.1 189925..190386(+) (comGF) [Streptococcus agalactiae strain SS1]
MKIIRKFCTYQKLRVKAFTLLKCLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=124796 RDF_RS01110 WP_001878820.1 189925..190386(+) (comGF) [Streptococcus agalactiae strain SS1]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAAAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.183	92.81	0.438
comGF	Streptococcus mutans UA140	47.183	92.81	0.438
comGF/cglF	Streptococcus pneumoniae Rx1	42.446	90.85	0.386
comGF/cglF	Streptococcus pneumoniae D39	42.446	90.85	0.386
comGF/cglF	Streptococcus pneumoniae R6	42.446	90.85	0.386
comGF/cglF	Streptococcus pneumoniae TIGR4	42.446	90.85	0.386
comGF/cglF	Streptococcus mitis SK321	43.284	87.582	0.379
comGF/cglF	Streptococcus mitis NCTC 12261	42.537	87.582	0.373
comGF	Lactococcus lactis subsp. cremoris KW2	40	91.503	0.366