Detailed information NTG0123973

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: C645_RS05925
• Genome accession: NZ_CP008740
• Coordinates: 1151349..1152470 (-)
• Length: 373 a.a.
• NCBI ID: WP_005688367.1
• Uniprot ID: -
• Organism: Haemophilus influenzae 2019
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1146349..1157470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C645_RS05895 (C645_05970)	dusB	1146793..1147773 (+)	981	WP_012055332.1	tRNA dihydrouridine synthase DusB	-
C645_RS05900 (C645_05975)	fis	1147767..1148066 (+)	300	WP_005651583.1	DNA-binding transcriptional regulator Fis	-
C645_RS05905 (C645_05980)	smpB	1148161..1148646 (-)	486	WP_005659251.1	SsrA-binding protein SmpB	-
C645_RS05910 (C645_05985)	pfkA	1148885..1149850 (-)	966	WP_005659252.1	6-phosphofructokinase	-
C645_RS05915 (C645_05990)	-	1149946..1150527 (-)	582	WP_005651586.1	hypothetical protein	-
C645_RS05920 (C645_05995)	yaaA	1150520..1151296 (-)	777	WP_005688368.1	peroxide stress protein YaaA	-
C645_RS05925 (C645_06000)	dprA	1151349..1152470 (-)	1122	WP_005688367.1	DNA-processing protein DprA	Machinery gene
C645_RS05930 (C645_06005)	leuA	1153028..1154575 (+)	1548	WP_005655964.1	2-isopropylmalate synthase	-
C645_RS05935 (C645_06010)	leuB	1154661..1155737 (+)	1077	WP_005688366.1	3-isopropylmalate dehydrogenase	-
C645_RS05940 (C645_06015)	leuC	1155814..1157223 (+)	1410	WP_005655967.1	3-isopropylmalate dehydratase large subunit	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41665.74 Da
• Isoelectric Point: 6.3039

>NTDB_id=123973 C645_RS05925 WP_005688367.1 1151349..1152470(-) (dprA) [Haemophilus influenzae 2019]
MNDITYTLLRLMQVPKLGGVGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALAWSQKEGNHLVNY
FSPFYPFLLKQTANFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGYCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=123973 C645_RS05925 WP_005688367.1 1151349..1152470(-) (dprA) [Haemophilus influenzae 2019]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTACCTAAACTTGGCGGCGTTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAATTATGATGATGTTGCTTTCCGACAAATGGGGTGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAACCTGAAGCAAAATTTATTGAGCCAGCACTCGCGTGGTCACAAAAAGAGGGAAATCATTTAGTGAATTAT
TTTTCCCCTTTTTATCCCTTTTTATTGAAACAGACCGCAAACTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCACAACGCCAAATGGCAATGGTTGGGAGCCGTTATTGCACGACTTATGGAGAATATTGGGCAAAACATTTTGCAA
CAGAACTTTCATTAGCGGGTTTTACCATAACAAGCGGTTTAGCATTAGGAATTGATGGTTATTGTCATCAGGCTGTCGTT
AATATTCAAGGGCAAACTATTGCGGTCTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCAGC
ACAAATCATCGAAAATAATGGCGCATTAGTCTCTGAATTTTTACCAAACCAAGCACCTATTGCTGCTAATTTTCCACGCC
GTAATCGGATTATTAGTGGGCTTTCAGTCGGCACGCTTGTTGTTGAAGCCACCGAAAAAAGTGGATCACTTATTACTGCA
CGGTATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCAGGCAATATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTGATTAAACAAGGCGCAATGTTGGTAGAAAATGCAAAGGACATTTTGGAAACCCTCTACCAACATTCTATCCACAGCC
AAACTGAAATTGATTTTGACCAGATCGCCGTGCCTAATTACACGCCACCACCCGATCCTCGCCGATTAGTAGAAGCACCA
AGCCACCCGAAACTTTACTCGCGTATTGGTTACACGCCTGTGAGCATTGATGATTTAGCGGAAGAATTTAACTTGAGTGT
CGATGTTTTGCTTGTTCAGTTGCTCGATCTTGAGTTGCAAGATCTTATCATAAGTGAAAATGGCTTATATAAACGCGTTT
AA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (311-366)

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	98.928	100	0.989
dprA	Glaesserella parasuis strain SC1401	52.011	93.298	0.485
dprA	Vibrio campbellii strain DS40M4	43.351	100	0.437
dprA	Vibrio cholerae strain A1552	43.288	97.855	0.424
dprA	Legionella pneumophila strain ERS1305867	40.346	93.029	0.375