Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FE90_RS07950 Genome accession   NZ_CP008695
Coordinates   1565146..1565832 (-) Length   228 a.a.
NCBI ID   WP_002991052.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M23ND     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1560146..1570832
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE90_RS07930 (FE90_1601) dnaI 1560872..1561774 (-) 903 WP_038433694.1 primosomal protein DnaI -
  FE90_RS07935 (FE90_1602) - 1561775..1562950 (-) 1176 WP_030127140.1 replication initiation and membrane attachment family protein -
  FE90_RS07940 (FE90_1603) nrdR 1562934..1563428 (-) 495 WP_002985941.1 transcriptional regulator NrdR -
  FE90_RS07945 (FE90_1605) covS 1563643..1565140 (-) 1498 Protein_1567 two-component system sensor histidine kinase CovS -
  FE90_RS07950 (FE90_1606) covR 1565146..1565832 (-) 687 WP_002991052.1 two-component system response regulator CovR Regulator
  FE90_RS07955 (FE90_1607) - 1566099..1566632 (-) 534 WP_011054200.1 YceD family protein -
  FE90_RS07960 (FE90_1608) - 1566836..1567813 (+) 978 WP_038433695.1 IS30-like element IS1239 family transposase -
  FE90_RS07965 (FE90_1609) htpX 1567952..1568848 (-) 897 WP_002985953.1 zinc metalloprotease HtpX -
  FE90_RS07970 (FE90_1610) - 1568895..1569452 (-) 558 WP_002985956.1 LemA family protein -
  FE90_RS07975 (FE90_1611) rsmG 1569602..1570315 (+) 714 WP_002985957.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26618.70 Da        Isoelectric Point: 4.6586

>NTDB_id=123605 FE90_RS07950 WP_002991052.1 1565146..1565832(-) (covR) [Streptococcus pyogenes strain M23ND]
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=123605 FE90_RS07950 WP_002991052.1 1565146..1565832(-) (covR) [Streptococcus pyogenes strain M23ND]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAATCTGGCTAGATTCGTTTCTCTTGAGCTGCAACATGAGGGTTA
TGAAGTCATTGTTGAGGTCAATGGTCGCGAAGGGTTAGAAACTGCTTTGGAAAAAGAGTTTGATTTAATCCTGCTTGACT
TAATGTTACCAGAGATGGATGGTTTTGAAGTGACCCGTCGTTTGCAAACCGAAAAAACAACGTATATCATGATGATGACT
GCGCGTGATTCTATTATGGATGTGGTTGCAGGTTTAGACCGCGGTGCAGACGACTATATTGTTAAACCGTTTGCCATTGA
AGAACTACTTGCCCGTATTCGTGCTATTTTCCGCCGTCAAGATATTGAATCTGAGAAGAAAGTGCCTAGTCAAGGTATTT
ATCGAGATCTAGTTTTAAATCCACAAAACCGTTCAGTTAATCGTGGCGACGATGAGATTTCTCTCACTAAACGTGAATAT
GATTTGCTTAATATTTTGATGACTAACATGAATCGTGTCATGACACGTGAAGAATTATTGTCAAATGTTTGGAAATATGA
TGAAGCCGTTGAGACTAATGTTGTAGATGTCTATATTCGTTATCTCCGCGGCAAAATTGACATTCCAGGCAAGGAATCTT
ATATCCAAACAGTGCGTGGCATGGGATACGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.966

100

0.447
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment