Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   EG66_RS00200 Genome accession   NZ_CP007605
Coordinates   37449..38186 (+) Length   245 a.a.
NCBI ID   WP_038419556.1    Uniprot ID   -
Organism   Helicobacter pylori strain BM012B     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32449..43186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EG66_RS00175 (EG66_00200) panD 34616..34969 (+) 354 WP_023591491.1 aspartate 1-decarboxylase -
  EG66_RS00180 (EG66_00205) - 34972..35265 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  EG66_RS00185 (EG66_00210) - 35265..36260 (+) 996 WP_038419552.1 PDZ domain-containing protein -
  EG66_RS00190 (EG66_00215) comB6 36268..37323 (+) 1056 WP_038419554.1 P-type conjugative transfer protein TrbL Machinery gene
  EG66_RS00195 comB7 37339..37452 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  EG66_RS00200 (EG66_00225) comB8 37449..38186 (+) 738 WP_038419556.1 type IV secretion system protein Machinery gene
  EG66_RS00205 (EG66_00230) comB9 38186..39172 (+) 987 WP_038419558.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  EG66_RS00210 (EG66_00235) comB10 39165..40301 (+) 1137 WP_038419560.1 DNA type IV secretion system protein ComB10 Machinery gene
  EG66_RS00215 (EG66_00240) - 40372..41784 (+) 1413 WP_038419562.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  EG66_RS00220 (EG66_00245) gmd 41813..42958 (+) 1146 WP_038419564.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28484.66 Da        Isoelectric Point: 8.9546

>NTDB_id=121586 EG66_RS00200 WP_038419556.1 37449..38186(+) (comB8) [Helicobacter pylori strain BM012B]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIALSYLFDTPDFDYASMPKNPTGFKITRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=121586 EG66_RS00200 WP_038419556.1 37449..38186(+) (comB8) [Helicobacter pylori strain BM012B]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGGCTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAATCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTGAACCGAGAGAGTATTAATCGCATTGATGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGCAGCTAAACTTTTGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGCGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACCCGTTACAGCATCACTGAAATC
ACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.976

Multiple sequence alignment