Detailed information NTG0119962

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ZY05719_RS03195
• Genome accession: NZ_CP007497
• Coordinates: 635995..638232 (+)
• Length: 745 a.a.
• NCBI ID: WP_012775040.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ZY05719 isolate diseased pig
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 630995..643232

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ZY05719_RS03170 (ZY05719_03160)	-	631066..631995 (-)	930	WP_012775038.1	ABC transporter substrate-binding protein	-
ZY05719_RS03175 (ZY05719_03165)	-	632008..632793 (-)	786	WP_011922762.1	ABC transporter ATP-binding protein	-
ZY05719_RS03180 (ZY05719_03170)	-	632945..634390 (-)	1446	WP_011922188.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
ZY05719_RS03185 (ZY05719_03175)	-	634537..635286 (+)	750	WP_012775039.1	lysophospholipid acyltransferase family protein	-
ZY05719_RS03190 (ZY05719_03180)	-	635349..636011 (+)	663	WP_011922190.1	helix-hairpin-helix domain-containing protein	-
ZY05719_RS03195 (ZY05719_03185)	comEC/celB	635995..638232 (+)	2238	WP_012775040.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ZY05719_RS10725 (ZY05719_03190)	-	638249..638374 (+)	126	Protein_577	IS982 family transposase	-
ZY05719_RS03205 (ZY05719_03195)	-	638557..639213 (+)	657	WP_011922763.1	CBS domain-containing protein	-
ZY05719_RS03210 (ZY05719_03200)	-	639307..640134 (+)	828	WP_011922194.1	hypothetical protein	-
ZY05719_RS03215 (ZY05719_03205)	-	640140..641411 (+)	1272	WP_011922195.1	toxic anion resistance protein	-
ZY05719_RS03220 (ZY05719_03210)	-	641448..642314 (-)	867	WP_002935357.1	YitT family protein	-
ZY05719_RS03225 (ZY05719_03215)	tmk	642489..643127 (+)	639	WP_012775041.1	dTMP kinase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83965.92 Da
• Isoelectric Point: 7.8195

>NTDB_id=119962 ZY05719_RS03195 WP_012775040.1 635995..638232(+) (comEC/celB) [Streptococcus suis strain ZY05719 isolate diseased pig]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMCLLSLVLAVFGVRQGKTVFLKTLPLLTLCGLFFGCQKVQWERAAQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQNYQVFYKLTSQEEQTYFQNLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSTWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFICLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVKMTWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVLDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWKEWKIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=119962 ZY05719_RS03195 WP_012775040.1 635995..638232(+) (comEC/celB) [Streptococcus suis strain ZY05719 isolate diseased pig]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCAGCTTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGTGCCTGCTCAGCTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAACCCTGTGTGGTCTCTTTTTCGGATGCCAAAAGGTCCAATGGGAGCGGGCAGCTCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATAGACATCAATGGCGACAGCTTGTCTTTTCGTGGTCGGGC
TGATGGACAAAACTATCAGGTTTTCTACAAATTAACCAGTCAGGAGGAGCAGACCTATTTTCAAAATCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGCTGTCAACTTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAAC
AGTGGATAAGTTACAAATTCCCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAATTTTGCGGTGACGGTCTTTATCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACTTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTCTATCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTACTCTTGCCAGGTTTGTCAGTC
ATTTTTCTCCTGTCGCCAGTTGTCAAGATGACTTGGGTCAACGGATTTTTCGTCTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAATGAGGTGACGGTGCTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTAGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCGACCTTGAAAAAAATCAATGTTCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCATGGCTCCAAAGGCTCTTCTTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGACAGCCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAGGAGTGGAAGATTGAGACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (215-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.774	99.597	0.536
comEC/celB	Streptococcus mitis NCTC 12261	52.782	98.926	0.522
comEC/celB	Streptococcus pneumoniae TIGR4	51.973	98.658	0.513
comEC/celB	Streptococcus pneumoniae Rx1	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae D39	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae R6	51.701	98.658	0.51
comEC	Lactococcus lactis subsp. cremoris KW2	49.399	100	0.497