Detailed information NTG0119951

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: ZY05719_RS00805
• Genome accession: NZ_CP007497
• Coordinates: 122547..122981 (+)
• Length: 144 a.a.
• NCBI ID: WP_011922561.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ZY05719 isolate diseased pig
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 117547..127981

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ZY05719_RS00770 (ZY05719_00760)	-	118296..118661 (+)	366	WP_002936568.1	DUF1033 family protein	-
ZY05719_RS00775 (ZY05719_00765)	-	118696..119639 (-)	944	Protein_116	S66 peptidase family protein	-
ZY05719_RS00780 (ZY05719_00770)	comYA	119725..120675 (+)	951	WP_011921718.1	competence type IV pilus ATPase ComGA	Machinery gene
ZY05719_RS00785 (ZY05719_00775)	comYB	120587..121624 (+)	1038	WP_011921719.1	competence type IV pilus assembly protein ComGB	Machinery gene
ZY05719_RS00790 (ZY05719_00780)	comYC	121626..121907 (+)	282	WP_011921720.1	competence type IV pilus major pilin ComGC	Machinery gene
ZY05719_RS00795 (ZY05719_00785)	comGD	121888..122295 (+)	408	WP_011921721.1	competence type IV pilus minor pilin ComGD	-
ZY05719_RS00800 (ZY05719_00790)	comYE	122267..122560 (+)	294	WP_011921722.1	competence type IV pilus minor pilin ComGE	Machinery gene
ZY05719_RS00805 (ZY05719_00795)	comGF/cglF	122547..122981 (+)	435	WP_011922561.1	competence type IV pilus minor pilin ComGF	Machinery gene
ZY05719_RS00810 (ZY05719_00800)	comGG	122959..123369 (+)	411	WP_011921724.1	competence type IV pilus minor pilin ComGG	-
ZY05719_RS00815 (ZY05719_00805)	comYH	123426..124379 (+)	954	WP_011922562.1	class I SAM-dependent methyltransferase	Machinery gene
ZY05719_RS00820 (ZY05719_00810)	-	124429..125616 (+)	1188	WP_011921727.1	acetate kinase	-
ZY05719_RS00825 (ZY05719_00815)	-	125931..126482 (+)	552	WP_012774908.1	folate family ECF transporter S component	-
ZY05719_RS00830 (ZY05719_00820)	-	126538..127794 (+)	1257	WP_011921729.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16491.85 Da
• Isoelectric Point: 5.9234

>NTDB_id=119951 ZY05719_RS00805 WP_011922561.1 122547..122981(+) (comGF/cglF) [Streptococcus suis strain ZY05719 isolate diseased pig]
MLKSKIPAFTLLECLVVLVILSGSLLIFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGE
QALAFGKSWSDDFRKTNDRGQGYQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=119951 ZY05719_RS00805 WP_011922561.1 122547..122981(+) (comGF/cglF) [Streptococcus suis strain ZY05719 isolate diseased pig]
TTGTTAAAAAGTAAAATTCCTGCTTTTACACTCTTGGAATGTTTGGTGGTTCTAGTCATTCTGTCAGGTAGCCTCTTGAT
TTTTGAAGGCTTATCCAAATTACTAGTCCAGGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGCCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGGTGAA
CAGGCTTTGGCCTTTGGCAAGTCATGGTCGGATGATTTTCGGAAAACAAATGATAGAGGCCAGGGTTACCAACCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GAACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae Rx1	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae D39	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae R6	52.482	97.917	0.514
comGF/cglF	Streptococcus mitis NCTC 12261	52.985	93.056	0.493
comYF	Streptococcus mutans UA140	48.611	100	0.486
comYF	Streptococcus mutans UA159	47.917	100	0.479
comGF/cglF	Streptococcus mitis SK321	50	93.056	0.465
comGF	Lactococcus lactis subsp. cremoris KW2	45.39	97.917	0.444