Detailed information NTG0119759

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NTHI723_RS03115
• Genome accession: NZ_CP007472
• Coordinates: 654150..655271 (+)
• Length: 373 a.a.
• NCBI ID: WP_044364451.1
• Uniprot ID: A0AAJ8WAC2
• Organism: Haemophilus influenzae strain 723
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 649150..660271

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NTHI723_RS03100 (NTHI723_00626)	leuC	649336..650745 (-)	1410	WP_044364448.1	3-isopropylmalate dehydratase large subunit	-
NTHI723_RS03105 (NTHI723_00627)	leuB	650819..651895 (-)	1077	WP_044364449.1	3-isopropylmalate dehydrogenase	-
NTHI723_RS03110 (NTHI723_00628)	leuA	652059..653606 (-)	1548	WP_044364450.1	2-isopropylmalate synthase	-
NTHI723_RS03115 (NTHI723_00629)	dprA	654150..655271 (+)	1122	WP_044364451.1	DNA-processing protein DprA	Machinery gene
NTHI723_RS03120 (NTHI723_00630)	yaaA	655325..656101 (+)	777	WP_044364452.1	peroxide stress protein YaaA	-
NTHI723_RS03125 (NTHI723_00631)	-	656094..656675 (+)	582	WP_011272328.1	hypothetical protein	-
NTHI723_RS03130 (NTHI723_00632)	pfkA	656771..657736 (+)	966	WP_011272327.1	6-phosphofructokinase	-
NTHI723_RS03135 (NTHI723_00633)	smpB	657975..658460 (+)	486	WP_005647965.1	SsrA-binding protein SmpB	-
NTHI723_RS03140 (NTHI723_00634)	fis	658561..658860 (-)	300	WP_005647967.1	DNA-binding transcriptional regulator Fis	-
NTHI723_RS03145 (NTHI723_00635)	dusB	658854..659880 (-)	1027	Protein_637	tRNA dihydrouridine synthase DusB	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41612.68 Da
• Isoelectric Point: 6.4124

>NTDB_id=119759 NTHI723_RS03115 WP_044364451.1 654150..655271(+) (dprA) [Haemophilus influenzae strain 723]
MNDITYTLLRLMQVPKLGGVGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALAWSQKEGNHLVNY
FSPFYPFLLKQTASFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=119759 NTHI723_RS03115 WP_044364451.1 654150..655271(+) (dprA) [Haemophilus influenzae strain 723]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTACCTAAACTTGGCGGTGTTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAACTATGATGATGTTGCTTTCCGACAAATGGGATGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAACCTGAAGCAAAATTTATTGAGCCAGCACTTGCGTGGTCACAAAAAGAAGGAAATCATTTAGTAAATTAT
TTTTCCCCTTTTTATCCCTTTTTATTGAAACAGACCGCAAGTTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCGCAACGCCAAATGGCAATGGTTGGTAGCCGTTATTGCACGACTTATGGAGAATATTGGGCAAAACATTTTGCAA
CAGAACTTTCATTAGCGGGTTTTACCATAACAAGCGGTTTAGCATTAGGAATTGATGGTCATTGTCATCAAGCTGTCGTC
AATATTCAAGGACAAACTATTGCGGTTTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCGGC
ACAAATCATCGAAAATAATGGCGCATTAGTCTCTGAGTTCTTACCAAACCAAGCCCCCATTGCTGCTAATTTTCCACGTC
GAAATCGGATTATTAGTGGGCTTTCAGTCGGCACGCTTGTTGTTGAAGCCACCGAAAAAAGCGGATCACTTATTACTGCA
CGGTATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCAGGCAATATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTAATTAAACAAGGCGCAATGTTGGTAGAAAATGCAAAGGACATTTTGGAAACCCTCTACCAACATTCTATCCACAGCC
AAACTGAAATTGATTTTGACCAGATCGCCGTGCCTAATTACACGCCACCACCCGACCCTCGCCGATTAGTAGAAGCACCA
AGTCACCCGAAACTTTACTCACGTATTGGCTATACTCCTGTGAGCATTGATGATTTAGCTGAAGAATTTAATTTAAGTGT
CGATGTTTTACTTGTTCAATTGCTCGATCTTGAGCTACAAGATCTTATCATAAGTGAAAATGGCTTATATAAACGCGTTT
AA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

• DprA winged helix domain (DprA_WH) (311-366)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	99.464	100	0.995
dprA	Glaesserella parasuis strain SC1401	52.011	93.298	0.485
dprA	Vibrio campbellii strain DS40M4	43.617	100	0.44
dprA	Vibrio cholerae strain A1552	43.288	97.855	0.424
dprA	Legionella pneumophila strain ERS1305867	40.634	93.029	0.378