Detailed information NTG0119689

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NTHI477_RS03560
• Genome accession: NZ_CP007470
• Coordinates: 756388..757509 (+)
• Length: 373 a.a.
• NCBI ID: WP_005655963.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain 477
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 751388..762509

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NTHI477_RS03545 (NTHI477_00721)	leuC	751470..752879 (-)	1410	WP_044330776.1	3-isopropylmalate dehydratase large subunit	-
NTHI477_RS03550 (NTHI477_00722)	leuB	753056..754132 (-)	1077	WP_044330779.1	3-isopropylmalate dehydrogenase	-
NTHI477_RS03555 (NTHI477_00723)	leuA	754296..755843 (-)	1548	WP_044330782.1	2-isopropylmalate synthase	-
NTHI477_RS03560 (NTHI477_00724)	dprA	756388..757509 (+)	1122	WP_005655963.1	DNA-processing protein DprA	Machinery gene
NTHI477_RS03565 (NTHI477_00725)	yaaA	757562..758338 (+)	777	WP_005655962.1	peroxide stress protein YaaA	-
NTHI477_RS03570 (NTHI477_00726)	-	758331..758912 (+)	582	WP_005655961.1	hypothetical protein	-
NTHI477_RS03575 (NTHI477_00727)	pfkA	759008..759973 (+)	966	WP_005655960.1	6-phosphofructokinase	-
NTHI477_RS03580 (NTHI477_00728)	smpB	760212..760697 (+)	486	WP_044330784.1	SsrA-binding protein SmpB	-
NTHI477_RS03585 (NTHI477_00729)	fis	760792..761091 (-)	300	WP_005651583.1	DNA-binding transcriptional regulator Fis	-
NTHI477_RS03590 (NTHI477_00730)	dusB	761085..762065 (-)	981	WP_006995627.1	tRNA dihydrouridine synthase DusB	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41640.74 Da
• Isoelectric Point: 6.4124

>NTDB_id=119689 NTHI477_RS03560 WP_005655963.1 756388..757509(+) (dprA) [Haemophilus influenzae strain 477]
MNDITYTLLRLMQVPKLGGVGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALVWSQKEGNHLVNY
FSPFYPFLLKQTASFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=119689 NTHI477_RS03560 WP_005655963.1 756388..757509(+) (dprA) [Haemophilus influenzae strain 477]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTACCTAAACTTGGCGGCGTTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAATTATGATGATGTTGCTTTCCGACAAATGGGGTGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAGCCTGAAGCAAAATTTATTGAGCCTGCACTTGTGTGGTCACAAAAAGAGGGAAATCATTTAGTGAATTAT
TTTTCCCCTTTTTATCCCTTTTTGTTGAAACAGACCGCAAGTTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCACAACGCCAAATGGCAATGGTTGGAAGCCGTTATTGCACGACTTACGGAGAATATTGGGCAAAACATTTTGCGA
CAGAACTTTCATTAGCTGGCTTTACGATTACTAGTGGACTTGCATTAGGAATTGATGGACATTGCCATCAAGCTGTCGTC
AATATTCAAGGACAAACTATTGCGGTTTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCAGC
ACAAATCATCGAAAATAATGGCGCATTAGTCTCTGAGTTCTTACCAAACCAAGCCCCCATTGCCGCTAATTTCCCACGTC
GTAATCGGATTATTAGCGGGCTTTCAGTTGGCACGCTTGTTGTTGAAGCCACAGAAAAAAGCGGCTCGCTTATTACTGCG
CGATATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCGGGAAACATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTAATTAAACAAGGTGCAATGTTAGTAGAAAATGCTAAAGATATTTTGGAAACCCTCTACCAACATTCTATCCATAGCC
AAACTGAAATCGATTTTGACCAGATCGCCGTGCCTAATTACACGCCACCACCTGATCCTCGTCGATTAGTAGAAGCACCA
AGCCACCCGAAACTTTATTCGCGTATTGGTTACACGCCTGTGAGCATTGATGATTTAGCGGAAGAATTTAATTTAAGCGT
CGATGTTTTGCTTGTTCAGTTGCTCGATCTTGAGTTGCAAGATCTTATCATAAGTGAAAATGGGTTATATAAACGCGTTT
AG

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (311-366)

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	99.732	100	0.997
dprA	Glaesserella parasuis strain SC1401	52.011	93.298	0.485
dprA	Vibrio campbellii strain DS40M4	43.617	100	0.44
dprA	Vibrio cholerae strain A1552	43.288	97.855	0.424
dprA	Legionella pneumophila strain ERS1305867	40.634	93.029	0.378