Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   STAB1101_RS01495 Genome accession   NZ_CP007240
Coordinates   282610..283296 (+) Length   228 a.a.
NCBI ID   WP_002991052.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 7F7     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 277610..288296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAB1101_RS01470 (STAB1101_01470) ktrB 277753..279129 (-) 1377 WP_038431719.1 potassium uptake transporter channel subunit KtrB -
  STAB1101_RS01475 (STAB1101_01475) rsmG 279213..279926 (-) 714 WP_014407313.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STAB1101_RS01480 (STAB1101_01480) - 280076..280633 (+) 558 WP_038431211.1 LemA family protein -
  STAB1101_RS01485 (STAB1101_01485) htpX 280680..281576 (+) 897 WP_002985953.1 zinc metalloprotease HtpX -
  STAB1101_RS01490 (STAB1101_01490) - 281810..282343 (+) 534 WP_014635288.1 YceD family protein -
  STAB1101_RS01495 (STAB1101_01495) covR 282610..283296 (+) 687 WP_002991052.1 two-component system response regulator CovR Regulator
  STAB1101_RS01500 (STAB1101_01500) covS 283302..284804 (+) 1503 WP_002991036.1 two-component system sensor histidine kinase CovS -
  STAB1101_RS01505 (STAB1101_01505) nrdR 285019..285513 (+) 495 WP_002985941.1 transcriptional regulator NrdR -
  STAB1101_RS01510 (STAB1101_01510) - 285497..286672 (+) 1176 WP_009880401.1 replication initiation and membrane attachment family protein -
  STAB1101_RS01515 (STAB1101_01515) dnaI 286673..287575 (+) 903 WP_002991016.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26618.70 Da        Isoelectric Point: 4.6586

>NTDB_id=118023 STAB1101_RS01495 WP_002991052.1 282610..283296(+) (covR) [Streptococcus pyogenes strain 7F7]
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=118023 STAB1101_RS01495 WP_002991052.1 282610..283296(+) (covR) [Streptococcus pyogenes strain 7F7]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAATCTGGCTAGATTCGTTTCTCTTGAGCTGCAACATGAGGGTTA
TGAAGTCATTGTTGAGGTCAATGGTCGTGAAGGGTTAGAAACTGCTTTGGAAAAAGAGTTTGATTTAATCCTGCTTGACT
TAATGTTACCAGAGATGGATGGTTTTGAAGTGACCCGTCGTTTGCAAACCGAAAAAACAACGTATATCATGATGATGACT
GCGCGTGATTCTATTATGGATGTGGTTGCAGGTTTAGACCGCGGTGCAGACGACTATATTGTTAAACCGTTTGCCATTGA
AGAACTACTTGCCCGTATTCGTGCTATTTTCCGCCGTCAAGATATTGAATCTGAGAAGAAAGTGCCTAGTCAAGGTATTT
ATCGAGATCTAGTTTTAAATCCACAAAACCGTTCAGTTAATCGTGGCGACGATGAGATTTCTCTCACTAAACGTGAATAT
GATTTGCTTAATATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAATTATTGTCAAATGTTTGGAAATATGA
TGAAGCCGTTGAGACTAATGTTGTAGATGTCTATATTCGTTATCTCCGCGGCAAAATTGACATTCCAGGCAAGGAATCTT
ATATCCAAACAGTGCGTGGCATGGGATACGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.966

100

0.447
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment