Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DYB47_RS08445 Genome accession   NZ_UHFV01000002
Coordinates   1676064..1676753 (-) Length   229 a.a.
NCBI ID   WP_003082300.1    Uniprot ID   G5JUY6
Organism   Streptococcus macacae NCTC 11558     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1671064..1681753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS09810 - 1671450..1671581 (-) 132 WP_003081639.1 Blp family class II bacteriocin -
  DYB47_RS08425 (NCTC11558_01706) der 1672082..1673392 (-) 1311 WP_003079681.1 ribosome biogenesis GTPase Der -
  DYB47_RS08430 (NCTC11558_01707) dnaI 1673404..1674306 (-) 903 WP_003080396.1 primosomal protein DnaI -
  DYB47_RS08435 (NCTC11558_01708) - 1674307..1675482 (-) 1176 WP_003078553.1 DnaD domain protein -
  DYB47_RS08440 (NCTC11558_01709) nrdR 1675469..1675960 (-) 492 WP_003079923.1 transcriptional regulator NrdR -
  DYB47_RS08445 (NCTC11558_01710) covR 1676064..1676753 (-) 690 WP_003082300.1 response regulator transcription factor Regulator
  DYB47_RS08450 (NCTC11558_01711) - 1677099..1677632 (-) 534 WP_003081737.1 YceD family protein -
  DYB47_RS08455 (NCTC11558_01712) - 1677678..1678574 (-) 897 WP_003080387.1 cation diffusion facilitator family transporter -
  DYB47_RS08460 (NCTC11558_01713) htpX 1678693..1679592 (-) 900 WP_003082219.1 zinc metalloprotease HtpX -
  DYB47_RS08465 (NCTC11558_01714) - 1679602..1680162 (-) 561 WP_003078840.1 LemA family protein -
  DYB47_RS08470 (NCTC11558_01715) rsmG 1680256..1680969 (+) 714 WP_003080553.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26513.47 Da        Isoelectric Point: 4.9732

>NTDB_id=1171338 DYB47_RS08445 WP_003082300.1 1676064..1676753(-) (covR) [Streptococcus macacae NCTC 11558]
MAKSILIIEDEKNLAKFVSLELQHEGYEVEVEHDGRSGLNKALEKDYDLILLDLMLPEMDGYEVTRRLQLEKTTYVIMVT
ARDSVMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKYVTKPDGTYRDLQLDVHNRAAIRNGETIPLTKRE
FDLLSVLMENINQVMTREELLAHVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYVQTVRGMGYVIRDK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1171338 DYB47_RS08445 WP_003082300.1 1676064..1676753(-) (covR) [Streptococcus macacae NCTC 11558]
ATGGCAAAAAGTATTTTAATTATTGAAGACGAAAAGAATTTAGCAAAATTTGTTTCCTTGGAACTGCAGCACGAAGGTTA
TGAGGTCGAAGTTGAACATGACGGCCGATCAGGACTAAATAAAGCTCTTGAAAAAGATTATGATCTAATCCTTTTGGATT
TGATGCTGCCGGAGATGGACGGCTATGAGGTAACGCGCCGCCTGCAGCTGGAGAAAACAACATATGTGATTATGGTAACG
GCCCGTGATTCTGTTATGGATATCGTAACAGGGTTGGATCGTGGTGCTGATGGCTATATTGTGAAACCATTTGCTATTGA
GGAATTACTAGCACGTGTACGTGCTATTTTTCGGCGGCAGGATATTGAAAAAGCTAAATATGTCACTAAGCCAGATGGAA
CCTATCGGGATTTACAGCTTGATGTACACAATAGAGCAGCTATTCGAAATGGAGAAACTATTCCATTGACGAAACGAGAG
TTTGATCTTTTGAGTGTTTTGATGGAAAATATCAATCAAGTAATGACCAGAGAAGAGTTGCTGGCACATGTCTGGAAATA
CGATCAAGAAGCAGAGACAAATGTTGTTGATGTCTATATTCGTTATCTGCGCGGGAAAATTGATGTTCCTGGAAAAGAAA
GCTATGTTCAGACTGTCCGCGGTATGGGCTATGTCATTCGTGATAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JUY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

76.856

100

0.769
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.755

100

0.638
  vicR Streptococcus mutans UA159

43.723

100

0.441
  micA Streptococcus pneumoniae Cp1015

40.693

100

0.41

Multiple sequence alignment