Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DYB47_RS05290 Genome accession   NZ_UHFV01000002
Coordinates   1023218..1024531 (-) Length   437 a.a.
NCBI ID   WP_003079730.1    Uniprot ID   -
Organism   Streptococcus macacae NCTC 11558     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1018218..1029531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS05260 (NCTC11558_01062) - 1018853..1019239 (-) 387 WP_003080758.1 cytidine deaminase -
  DYB47_RS05265 (NCTC11558_01063) deoC 1019229..1019891 (-) 663 WP_003078957.1 deoxyribose-phosphate aldolase -
  DYB47_RS05270 (NCTC11558_01064) - 1019910..1021187 (-) 1278 WP_003080077.1 pyrimidine-nucleoside phosphorylase -
  DYB47_RS05275 (NCTC11558_01065) - 1021174..1021773 (-) 600 WP_003082322.1 class I SAM-dependent methyltransferase -
  DYB47_RS05280 (NCTC11558_01066) coaA 1021866..1022786 (+) 921 WP_003078607.1 type I pantothenate kinase -
  DYB47_RS05285 (NCTC11558_01067) rpsT 1022840..1023091 (+) 252 WP_081479315.1 30S ribosomal protein S20 -
  DYB47_RS05290 (NCTC11558_01068) ciaH 1023218..1024531 (-) 1314 WP_003079730.1 sensor histidine kinase Regulator
  DYB47_RS05295 (NCTC11558_01069) ciaR 1024521..1025195 (-) 675 WP_003081988.1 response regulator transcription factor Regulator
  DYB47_RS05300 (NCTC11558_01070) - 1025364..1027910 (-) 2547 WP_003080305.1 M1 family metallopeptidase -
  DYB47_RS05305 (NCTC11558_01071) phoU 1027953..1028606 (-) 654 WP_003078547.1 phosphate signaling complex protein PhoU -
  DYB47_RS05310 (NCTC11558_01072) pstB 1028629..1029387 (-) 759 WP_003080953.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 50147.89 Da        Isoelectric Point: 10.1385

>NTDB_id=1171317 DYB47_RS05290 WP_003079730.1 1023218..1024531(-) (ciaH) [Streptococcus macacae NCTC 11558]
MLTRLRKKTSGENITFFGHFFAVFTGIFLVMTIIIIQVMQFGIYSSVDNSLKTAKGNIEDYVTMNMSHGVILPDGSEEES
GFPFKVKTNGEMAANTDTILYDKKHRVLNSINAFSSLYRIRPQLSEIGEIVQQKTKNVYGQTETYRTITVKVKSRFYPKV
KFATIVVNTTQLEQANKRYVSIIITVMIVFWFISVFASFYLAKWSRKPILENYERQKSFVENASHELRTPLAVLQNRLES
LFRKPEATIFDSSESIASSLEEVRNMRLLTTNLLNLARRDDGIEPELADIQPIFFEEIFRNFQMIAEENGKALHIKNKVN
RSIKTDKTLLKQLMTILFDNAVKYTDNNGEIWIDLKTTDRNLFFSVSDNGPGIADEDKKKIFDRFYRVDKARTRQKGGLG
LGLSLAKQITDSLKGSILIKDRKPQGTIFEVRITLNK

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=1171317 DYB47_RS05290 WP_003079730.1 1023218..1024531(-) (ciaH) [Streptococcus macacae NCTC 11558]
ATGCTAACTAGATTAAGAAAAAAAACATCAGGAGAAAATATCACCTTTTTTGGTCATTTCTTTGCTGTATTTACAGGTAT
ATTTCTTGTAATGACCATTATTATCATACAGGTTATGCAATTTGGAATTTATTCTTCTGTAGATAATAGTCTAAAAACGG
CAAAAGGAAATATTGAAGATTATGTAACCATGAATATGTCTCATGGTGTCATTTTGCCAGACGGATCAGAGGAGGAGAGT
GGTTTTCCCTTCAAAGTAAAAACAAATGGAGAAATGGCAGCTAATACAGATACCATTTTATATGATAAAAAACACCGTGT
TCTTAATAGTATTAATGCTTTCTCATCTCTTTACCGTATTCGCCCCCAATTAAGTGAAATCGGTGAAATAGTTCAGCAGA
AAACTAAGAATGTCTATGGTCAGACCGAAACTTATCGCACAATTACTGTCAAGGTCAAGAGCCGCTTTTACCCTAAGGTA
AAATTTGCTACTATTGTCGTTAATACAACGCAGCTTGAACAGGCTAACAAGCGTTATGTATCTATCATTATTACTGTCAT
GATTGTTTTTTGGTTTATTTCCGTTTTTGCAAGTTTTTATTTAGCTAAATGGAGCCGAAAGCCTATTTTGGAAAATTATG
AAAGGCAGAAATCTTTTGTTGAAAACGCTAGTCATGAATTAAGAACTCCCTTGGCAGTTTTACAGAATCGTTTGGAAAGT
CTCTTTCGAAAACCAGAGGCAACCATCTTTGATTCTTCAGAATCTATAGCCTCAAGCTTAGAAGAAGTTAGGAATATGCG
CCTTTTAACAACAAATCTGTTGAATTTAGCGCGTCGTGATGATGGTATTGAACCAGAGTTAGCAGATATACAGCCGATTT
TCTTCGAGGAAATTTTTAGGAATTTTCAAATGATTGCTGAAGAAAATGGGAAAGCCCTGCATATAAAAAATAAAGTCAAC
CGATCGATTAAAACAGATAAAACTTTGCTGAAGCAGCTTATGACAATTTTGTTTGATAATGCTGTTAAATATACTGATAA
TAATGGTGAGATTTGGATAGACCTTAAAACGACTGACCGTAATTTATTTTTCTCTGTTTCTGATAACGGACCTGGTATAG
CAGATGAAGATAAAAAGAAAATTTTTGATCGTTTTTATCGTGTTGATAAAGCAAGAACACGGCAGAAGGGAGGACTAGGC
TTAGGTCTCTCCTTAGCTAAGCAAATTACGGATAGCTTGAAAGGAAGTATTCTTATAAAGGACAGAAAACCGCAAGGAAC
TATCTTTGAAGTCCGTATAACACTCAATAAGTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(217-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

77.117

100

0.771
  ciaH Streptococcus pneumoniae Rx1

53.899

99.771

0.538
  ciaH Streptococcus pneumoniae D39

53.899

99.771

0.538
  ciaH Streptococcus pneumoniae R6

53.899

99.771

0.538
  ciaH Streptococcus pneumoniae TIGR4

53.899

99.771

0.538

Multiple sequence alignment