Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACLV7W_RS08695 Genome accession   NZ_OZ217346
Coordinates   1793439..1794176 (-) Length   245 a.a.
NCBI ID   WP_411865819.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis D22     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1788439..1799176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS08680 (SMID22_17900) - 1790467..1791828 (+) 1362 WP_223340332.1 bacteriocin secretion accessory protein -
  ACLV7W_RS08685 (SMID22_17910) blpC 1791885..1792040 (+) 156 WP_223340333.1 quorum-sensing system pheromone BlpC -
  ACLV7W_RS08690 (SMID22_17920) - 1792085..1793425 (-) 1341 WP_261029338.1 sensor histidine kinase -
  ACLV7W_RS08695 (SMID22_17930) comE/blpR 1793439..1794176 (-) 738 WP_411865819.1 response regulator transcription factor Regulator
  ACLV7W_RS08700 (SMID22_17940) - 1794181..1794519 (-) 339 WP_125393115.1 LytTR family DNA-binding domain-containing protein -
  ACLV7W_RS08705 (SMID22_17950) - 1794796..1795125 (+) 330 WP_411865820.1 helicase BlpT -
  ACLV7W_RS08710 (SMID22_17960) - 1795188..1796237 (-) 1050 WP_411865821.1 ABC transporter permease -
  ACLV7W_RS08715 (SMID22_17970) pptA 1796234..1796965 (-) 732 WP_000889954.1 ABC transporter ATP-binding protein Regulator
  ACLV7W_RS08720 (SMID22_17980) - 1797033..1797443 (+) 411 WP_001278317.1 HIT family protein -
  ACLV7W_RS08725 (SMID22_17990) - 1797453..1797740 (+) 288 WP_411865822.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28826.96 Da        Isoelectric Point: 6.6609

>NTDB_id=1170457 ACLV7W_RS08695 WP_411865819.1 1793439..1794176(-) (comE/blpR) [Streptococcus mitis isolate S. mitis D22]
MRIFVLEDDFSQQTRIETTIVKLLKEHHITPSSFEIFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALRYANSQDGKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLFHCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1170457 ACLV7W_RS08695 WP_411865819.1 1793439..1794176(-) (comE/blpR) [Streptococcus mitis isolate S. mitis D22]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGTGAAACTTTTGAAAGAACA
TCATATCACTCCCAGCTCTTTTGAGATCTTTGGCAAGCCAGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCGCATC
AACTATTCTTTTTGGACATTGAGATTCGAAATGAGGAGATGAAAGGTCTAGAGGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTACATTGATAAGGCCTTGTCGGCAGAGGAGTTTGAATCTCGGATCGAGACAGCCCTCCGCTATGCCAATAGTCAAGATG
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCGCCTAGAGCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACGGCGAGTTTAGAGGA
GGTTTTTAAGCAGGAACCCCGTCTCTTTCATTGCCACCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTCCTTTTCTTTCCCAATGGTGGAAGCTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATCAATAACTTACACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

55.738

99.592

0.555
  comE/comE1 Streptococcus equinus JB1

42.616

96.735

0.412
  comE/comE2 Streptococcus equinus JB1

39.256

98.776

0.388

Multiple sequence alignment