Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   ACLV7W_RS07900 Genome accession   NZ_OZ217346
Coordinates   1656329..1656988 (+) Length   219 a.a.
NCBI ID   WP_411865755.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis D22     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1651329..1661988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS07880 (SMID22_16270) - 1651425..1652513 (-) 1089 WP_084881667.1 AI-2E family transporter -
  ACLV7W_RS07885 (SMID22_16280) - 1652523..1653812 (-) 1290 WP_411865752.1 DUF308 domain-containing protein -
  ACLV7W_RS07890 (SMID22_16290) - 1654611..1655756 (+) 1146 WP_411865753.1 low temperature requirement protein A -
  ACLV7W_RS07895 (SMID22_16300) - 1655804..1656259 (-) 456 WP_411865754.1 GNAT family N-acetyltransferase -
  ACLV7W_RS07900 (SMID22_16310) cclA/cilC 1656329..1656988 (+) 660 WP_411865755.1 prepilin peptidase Machinery gene
  ACLV7W_RS07905 (SMID22_16320) trpA 1656960..1657736 (-) 777 WP_411865756.1 tryptophan synthase subunit alpha -
  ACLV7W_RS07910 (SMID22_16330) trpB 1657729..1658952 (-) 1224 WP_411865757.1 tryptophan synthase subunit beta -
  ACLV7W_RS07915 (SMID22_16340) - 1658930..1659529 (-) 600 WP_411865758.1 phosphoribosylanthranilate isomerase -
  ACLV7W_RS07920 (SMID22_16350) trpC 1659516..1660283 (-) 768 WP_411865759.1 indole-3-glycerol phosphate synthase TrpC -
  ACLV7W_RS07925 (SMID22_16360) trpD 1660280..1661284 (-) 1005 WP_411865760.1 anthranilate phosphoribosyltransferase -
  ACLV7W_RS07930 (SMID22_16370) - 1661295..1661861 (-) 567 WP_000601909.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24861.03 Da        Isoelectric Point: 7.6655

>NTDB_id=1170454 ACLV7W_RS07900 WP_411865755.1 1656329..1656988(+) (cclA/cilC) [Streptococcus mitis isolate S. mitis D22]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISPASHCDSCQTRLRPLDLIPILSQVFHRFRCRYCKAPYPVWYVLFELGLG
LLFLSWSWGLLSLSQVILITGGLTLGIYDFHHQEYPLLVWMTFHLILMASTGWNLVMVFFLVLGMLAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1170454 ACLV7W_RS07900 WP_411865755.1 1656329..1656988(+) (cclA/cilC) [Streptococcus mitis isolate S. mitis D22]
ATGATTGATTTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGCTTTCCAGAGCA
ATCCATTATCAGTCCAGCAAGTCACTGCGATTCCTGTCAGACTCGCTTGCGCCCCTTAGATTTGATTCCGATTCTCTCGC
AGGTCTTTCATCGCTTTCGCTGTCGCTACTGCAAGGCTCCTTATCCAGTCTGGTATGTCCTTTTTGAACTAGGCTTAGGA
CTCCTCTTTCTATCTTGGTCTTGGGGATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGGTGGCTTGACCTTAGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTCATGGCTTCCACTGGCTGGA
ATCTGGTCATGGTCTTCTTCCTTGTCCTTGGAATGTTAGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTTCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACCGAATTACTTATCTTGATTCAGTTTGCTTCTGCGACAGGAATTCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGGCTTCCTTTTGTGCCTTTCCTCTTACTCGCTGCTTGCGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

93.151

100

0.932
  cclA/cilC Streptococcus pneumoniae Rx1

92.694

100

0.927
  cclA/cilC Streptococcus pneumoniae D39

92.694

100

0.927
  cclA/cilC Streptococcus pneumoniae R6

92.694

100

0.927
  cclA/cilC Streptococcus pneumoniae TIGR4

90.411

100

0.904
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877

Multiple sequence alignment