Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   ACLV7W_RS05725 Genome accession   NZ_OZ217346
Coordinates   1179445..1180803 (-) Length   452 a.a.
NCBI ID   WP_411865611.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis D22     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1174445..1185803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS05695 (SMID22_11700) - 1175020..1176738 (+) 1719 WP_227325820.1 phospho-sugar mutase -
  ACLV7W_RS05700 (SMID22_11710) - 1176850..1177197 (+) 348 WP_411865610.1 thioredoxin -
  ACLV7W_RS05705 (SMID22_11720) - 1177235..1178008 (-) 774 WP_049544233.1 potassium channel family protein -
  ACLV7W_RS05710 (SMID22_11730) - 1178054..1178308 (-) 255 WP_004254226.1 type II toxin-antitoxin system RelE family toxin -
  ACLV7W_RS05715 (SMID22_11740) relB 1178310..1178552 (-) 243 WP_000208079.1 type II toxin-antitoxin system RelB family antitoxin -
  ACLV7W_RS05720 (SMID22_11750) vicX 1178643..1179452 (-) 810 WP_004254224.1 MBL fold metallo-hydrolase Regulator
  ACLV7W_RS05725 (SMID22_11760) micB 1179445..1180803 (-) 1359 WP_411865611.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACLV7W_RS05730 (SMID22_11770) micA 1180796..1181503 (-) 708 WP_000722072.1 response regulator YycF Regulator
  ACLV7W_RS05735 (SMID22_11780) mutY 1181559..1182734 (-) 1176 WP_411865612.1 A/G-specific adenine glycosylase -
  ACLV7W_RS05740 (SMID22_11790) pta 1182817..1183791 (-) 975 WP_000451580.1 phosphate acetyltransferase -
  ACLV7W_RS05745 (SMID22_11800) - 1183835..1184731 (-) 897 WP_084930135.1 RluA family pseudouridine synthase -
  ACLV7W_RS05750 (SMID22_11810) - 1184728..1185546 (-) 819 WP_049544217.1 NAD kinase -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 51949.34 Da        Isoelectric Point: 4.6533

>NTDB_id=1170446 ACLV7W_RS05725 WP_411865611.1 1179445..1180803(-) (micB) [Streptococcus mitis isolate S. mitis D22]
MIELIRKNILTSDFIFILILLGFILIVTLLLLENRRDNIRLKQINQKVKDLIAGDYSQVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQESKRLHSILSYMTDGVLATNRRGKITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LMIDSQDDNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDQIRGQDEEKKYELVRDYPITSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVTMKTTDDQMILSISDQGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEIEDQNE

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=1170446 ACLV7W_RS05725 WP_411865611.1 1179445..1180803(-) (micB) [Streptococcus mitis isolate S. mitis D22]
ATGATTGAATTGATTAGAAAAAATATTCTTACTAGTGATTTTATCTTCATTTTAATTTTATTGGGTTTTATCTTGATTGT
TACCTTGCTTTTGCTAGAAAATCGGCGAGATAATATTCGGTTGAAGCAAATTAATCAAAAAGTTAAAGACCTGATTGCAG
GAGATTATTCTCAGGTATTGGATATGCAGGGAAGCTCTGAAATCACTAATATTACCAATAATCTCAATGATTTATCAGAA
GTAATCCGCTTGACTCAAGAAAATCTGGAACAAGAGAGTAAACGATTGCACAGTATCCTCTCTTATATGACAGATGGAGT
CCTCGCGACCAATCGTCGTGGTAAGATTACTATGATTAATGACATGGCTAAGAAACAGCTAGGTGTTCAGAAAGAAGATG
TTCTCAATAAAAGTATTCTAGAATTGCTTAAGATTGAAGATGAGTATGAACTTCGTGATTTGATTACGCAGATTCCTGAA
CTCATGATTGATTCTCAGGATGACAATGGTGAATATCTGAGCCTTCGTGTACGCTTTGCCTTGGTCCGTCGAGAATCTGG
CTTTATCTCAGGTCTGGTTGCCGTTCTGCATGATACAACGGAGCAAGAGAAGGAAGAGCGCGAACGGAGACTCTTTGTTT
CTAACGTTAGTCATGAGTTACGGACTCCACTGACTAGTGTAAAATCCTATCTTGAAGCTTTGGATGAGGGAGCCTTGTCA
GAACCTGTTGCACCAGACTTTATTAAGGTATCTCTAGACGAAACCAATCGTATGATGCGCATGGTAACTGACCTCCTCCA
TCTCTCTCGAATTGACAATGCGACCAGTCATCTGGATGTGGAACTGATTAACTTCACTGCCTTTATTACTTTTATCCTCA
ACCGTTTTGATCAGATAAGAGGGCAGGATGAAGAGAAGAAATACGAACTGGTGAGAGATTACCCAATTACCTCTGTCTGG
ATTGAAATTGATACAGACAAGATGACACAGGTCATTGATAATATTCTTAACAATGCCATCAAGTATTCACCAGATGGTGG
GAAAATCACAGTGACCATGAAGACGACTGATGATCAGATGATTTTATCCATCTCAGACCAAGGTTTGGGTATTCCTAAGC
AGGATTTACCACGCATCTTTGACCGTTTTTACCGTGTGGATCGTGCTAGAAGTCGTGCCCAGGGTGGGACAGGTCTGGGA
CTGTCTATTGCTAAGGAAATTATCAAACAGCATAATGGCTTTATTTGGGCCAAGAGTGAATACGGTAAGGGATCAACTTT
CACAATTGTGCTCCCTTATGATAAGGATGCAGTGAAGGAAGAAGTATGGGAGGACGAAATAGAAGACCAGAATGAGTGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.977

97.124

0.874
  vicK Streptococcus mutans UA159

72.637

88.938

0.646

Multiple sequence alignment