Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   ACLV7W_RS05720 Genome accession   NZ_OZ217346
Coordinates   1178643..1179452 (-) Length   269 a.a.
NCBI ID   WP_004254224.1    Uniprot ID   A0A7X1V467
Organism   Streptococcus mitis isolate S. mitis D22     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1173643..1184452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS05695 (SMID22_11700) - 1175020..1176738 (+) 1719 WP_227325820.1 phospho-sugar mutase -
  ACLV7W_RS05700 (SMID22_11710) - 1176850..1177197 (+) 348 WP_411865610.1 thioredoxin -
  ACLV7W_RS05705 (SMID22_11720) - 1177235..1178008 (-) 774 WP_049544233.1 potassium channel family protein -
  ACLV7W_RS05710 (SMID22_11730) - 1178054..1178308 (-) 255 WP_004254226.1 type II toxin-antitoxin system RelE family toxin -
  ACLV7W_RS05715 (SMID22_11740) relB 1178310..1178552 (-) 243 WP_000208079.1 type II toxin-antitoxin system RelB family antitoxin -
  ACLV7W_RS05720 (SMID22_11750) vicX 1178643..1179452 (-) 810 WP_004254224.1 MBL fold metallo-hydrolase Regulator
  ACLV7W_RS05725 (SMID22_11760) micB 1179445..1180803 (-) 1359 WP_411865611.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACLV7W_RS05730 (SMID22_11770) micA 1180796..1181503 (-) 708 WP_000722072.1 response regulator YycF Regulator
  ACLV7W_RS05735 (SMID22_11780) mutY 1181559..1182734 (-) 1176 WP_411865612.1 A/G-specific adenine glycosylase -
  ACLV7W_RS05740 (SMID22_11790) pta 1182817..1183791 (-) 975 WP_000451580.1 phosphate acetyltransferase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29898.87 Da        Isoelectric Point: 6.1738

>NTDB_id=1170445 ACLV7W_RS05720 WP_004254224.1 1178643..1179452(-) (vicX) [Streptococcus mitis isolate S. mitis D22]
MSETGFKYSILASGSSGNSFYLETPKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDASQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIESNHDVEILRAGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGIDFKVYDTSPDTATPLTDI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=1170445 ACLV7W_RS05720 WP_004254224.1 1178643..1179452(-) (vicX) [Streptococcus mitis isolate S. mitis D22]
ATGAGTGAAACAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCCTTTTATCTGGAAACCCCAAAAAA
GAAACTTTTAGTGGATGCAGGCTTGTCGGGCAAGAAAATTACCAGCTTACTTGCTGAAATAAATCGCAAACCAGAGGACT
TGGATGCCATCTTGATTACGCATGAGCATTCTGACCATATTCATGGAGTGGGTGTTTTGGCTCGCAAGTATGGTATGGAT
TTGTACGCCAATGAAAAGACCTGGCAGGCTATGGAAAATAGCAAGTATCTTGGCAAGGTGGATGCCTCGCAAAAGCATAT
TTTTGAAATGGGCAAAACCAAAACATTTGGAGATATTGATATTGAGAGTTTTGGTGTTAGCCATGATGCGGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGACAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTTAGTGACCGTATGGCAGGA
ATTGTCGAGAATGCAGATGGCTATCTTATCGAGTCCAACCATGATGTAGAGATTTTGCGAGCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCGGATCTGGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGCACTAAGAAAATCTATCTTGGTCACTTGTCTAAGGAAAACAATATCAAGGAACTGGCTCACATGACCATGGTCAAT
CAGCTGGCGCAAGCTGATTTGGGAGTTGGAATAGACTTTAAAGTATATGATACTTCACCAGATACAGCAACACCATTGAC
AGATATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7X1V467

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

78.067

100

0.781

Multiple sequence alignment