Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   ACLV7D_RS04970 Genome accession   NZ_OZ217345
Coordinates   1040779..1042128 (+) Length   449 a.a.
NCBI ID   WP_050090938.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis F22     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1035779..1047128
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS04945 (SMIF22_09680) coaB 1035941..1036630 (-) 690 WP_218764539.1 phosphopantothenate--cysteine ligase -
  ACLV7D_RS04950 (SMIF22_09690) - 1036863..1038533 (+) 1671 WP_218764538.1 formate--tetrahydrofolate ligase -
  ACLV7D_RS04955 (SMIF22_09700) - 1038640..1038765 (-) 126 WP_001818232.1 hypothetical protein -
  ACLV7D_RS04960 (SMIF22_09710) mutY 1038851..1040026 (+) 1176 WP_172934919.1 A/G-specific adenine glycosylase -
  ACLV7D_RS04965 (SMIF22_09720) micA 1040082..1040786 (+) 705 WP_218764537.1 response regulator YycF Regulator
  ACLV7D_RS04970 (SMIF22_09730) micB 1040779..1042128 (+) 1350 WP_050090938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACLV7D_RS04975 (SMIF22_09740) vicX 1042130..1042939 (+) 810 WP_061387624.1 MBL fold metallo-hydrolase Regulator
  ACLV7D_RS04980 (SMIF22_09750) - 1043022..1043798 (+) 777 WP_112443739.1 potassium channel family protein -
  ACLV7D_RS04985 tnpA 1043953..1044417 (-) 465 Protein_932 IS200/IS605 family transposase -
  ACLV7D_RS04990 (SMIF22_09770) - 1044767..1045753 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51714.43 Da        Isoelectric Point: 4.9756

>NTDB_id=1170370 ACLV7D_RS04970 WP_050090938.1 1040779..1042128(+) (micB) [Streptococcus mitis isolate S. mitis F22]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIRLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEEDYELRDLITQSPE
LLLDSQDINGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1170370 ACLV7D_RS04970 WP_050090938.1 1040779..1042128(+) (micB) [Streptococcus mitis isolate S. mitis F22]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACTCTTCTATTACTGGAAAATAGACGTGATAATATTCGATTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGACTAAATAGTATTCTTTTTTATATGACAGATGGGGT
TCTTGCGACCAATCGTCGGGGGCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGCTGGTTAAAGAAGATG
TTCTGAATAGAAGCATTTTAGAATTGCTCAAGATAGAAGAAGACTATGAATTGCGTGATTTAATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGACATCAATGGCGAATATCTGAGCCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGAGCTTTGTGT
GAAACTGTAGCACCAGACTTCATCAAGGTGTCTCTGGACGAAACCAACCGTATGATGCGCATGGTGACGGACCTCCTTCA
TCTTTCACGGATTGATAACGCCACTAGTCACTTGGATGTGGAACTGATTAACTTCACTGCCTTTATTACTTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTAGTGAGGGATTATCCTATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCCATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCATGGTTTAGGCATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTTTATCGTGTGGATCGTGCTAGAAGTCGTGCCCAAGGTGGTACAGGTTTGGGA
CTGTCTATTGCCAAGGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGTAAGGGATCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(98-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.109

100

0.991
  vicK Streptococcus mutans UA159

69.652

89.532

0.624

Multiple sequence alignment