Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   ACLV7D_RS02330 Genome accession   NZ_OZ217345
Coordinates   445168..445827 (-) Length   219 a.a.
NCBI ID   WP_218764332.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis F22     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 440168..450827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS02300 (SMIF22_04450) - 440295..440861 (+) 567 WP_218764328.1 aminodeoxychorismate/anthranilate synthase component II -
  ACLV7D_RS02305 (SMIF22_04460) trpD 440872..441876 (+) 1005 WP_049516387.1 anthranilate phosphoribosyltransferase -
  ACLV7D_RS02310 (SMIF22_04470) trpC 441873..442640 (+) 768 WP_218764329.1 indole-3-glycerol phosphate synthase TrpC -
  ACLV7D_RS02315 (SMIF22_04480) - 442627..443226 (+) 600 WP_218764330.1 phosphoribosylanthranilate isomerase -
  ACLV7D_RS02320 (SMIF22_04490) trpB 443204..444427 (+) 1224 WP_061744376.1 tryptophan synthase subunit beta -
  ACLV7D_RS02325 (SMIF22_04500) trpA 444420..445196 (+) 777 WP_218764331.1 tryptophan synthase subunit alpha -
  ACLV7D_RS02330 (SMIF22_04510) cclA/cilC 445168..445827 (-) 660 WP_218764332.1 prepilin peptidase Machinery gene
  ACLV7D_RS02335 (SMIF22_04520) - 445897..446352 (+) 456 WP_218764333.1 GNAT family N-acetyltransferase -
  ACLV7D_RS02340 (SMIF22_04530) - 446402..447547 (-) 1146 WP_218764334.1 low temperature requirement protein A -
  ACLV7D_RS02345 (SMIF22_04540) - 448023..448538 (-) 516 WP_218764335.1 DUF308 domain-containing protein -
  ACLV7D_RS02350 (SMIF22_04550) - 448760..449119 (-) 360 WP_218764336.1 hypothetical protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24927.11 Da        Isoelectric Point: 7.2767

>NTDB_id=1170356 ACLV7D_RS02330 WP_218764332.1 445168..445827(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis F22]
MIDFYFFLVGSILASFLGLVIDRFPEQSIIQPASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKAPYPVWYALLELSLG
LLFLAWSWELLSLSQVILITAGLTLGIYDFHHQEYPLLVWMTFHLILMVSSGWNLVMVFFLVLGILAHFIDIRMGAGDFL
FLASCALIFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1170356 ACLV7D_RS02330 WP_218764332.1 445168..445827(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis F22]
ATGATTGATTTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCTGAGCA
ATCTATTATCCAACCTGCTAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCGC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGCTCCTTATCCAGTCTGGTATGCCCTTTTGGAACTAAGCTTAGGA
CTCCTCTTTCTGGCTTGGTCTTGGGAATTGCTTTCCTTGAGTCAAGTCATCCTAATCACTGCGGGTTTGACCTTGGGCAT
TTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTCATGGTTTCCTCTGGCTGGA
ATCTAGTCATGGTCTTCTTCCTTGTCCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTTCTC
TTTCTAGCTTCTTGCGCTCTTATCTTTAGCGTAACCGAATTACTCATCTTGATTCAGTTTGCTTCTGCGACAGGCATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTCTTACTCGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

93.151

100

0.932
  cclA/cilC Streptococcus pneumoniae Rx1

93.151

100

0.932
  cclA/cilC Streptococcus pneumoniae D39

93.151

100

0.932
  cclA/cilC Streptococcus pneumoniae R6

93.151

100

0.932
  cclA/cilC Streptococcus pneumoniae TIGR4

90.868

100

0.909
  cclA/cilC Streptococcus mitis NCTC 12261

88.128

100

0.881

Multiple sequence alignment