Detailed information NTG1170275

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: ACLV7A_RS02060
• Genome accession: NZ_OZ217344
• Coordinates: 398447..399106 (-)
• Length: 219 a.a.
• NCBI ID: WP_411863453.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis E22
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 393447..404106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7A_RS02030 (SMIE22_03930)	-	393574..394140 (+)	567	WP_411863448.1	aminodeoxychorismate/anthranilate synthase component II	-
ACLV7A_RS02035 (SMIE22_03940)	trpD	394151..395155 (+)	1005	WP_004256041.1	anthranilate phosphoribosyltransferase	-
ACLV7A_RS02040 (SMIE22_03950)	trpC	395152..395919 (+)	768	WP_411863449.1	indole-3-glycerol phosphate synthase TrpC	-
ACLV7A_RS02045 (SMIE22_03960)	-	395906..396505 (+)	600	WP_411863450.1	phosphoribosylanthranilate isomerase	-
ACLV7A_RS02050 (SMIE22_03970)	trpB	396483..397706 (+)	1224	WP_411863451.1	tryptophan synthase subunit beta	-
ACLV7A_RS02055 (SMIE22_03980)	trpA	397699..398475 (+)	777	WP_411863452.1	tryptophan synthase subunit alpha	-
ACLV7A_RS02060 (SMIE22_03990)	cclA/cilC	398447..399106 (-)	660	WP_411863453.1	prepilin peptidase	Machinery gene
ACLV7A_RS02065 (SMIE22_04000)	-	399176..399631 (+)	456	WP_411864203.1	GNAT family N-acetyltransferase	-
ACLV7A_RS02070 (SMIE22_04010)	-	399788..400666 (-)	879	WP_411863454.1	SDR family NAD(P)-dependent oxidoreductase	-
ACLV7A_RS02075 (SMIE22_04020)	-	400668..401504 (-)	837	WP_411863455.1	alpha/beta fold hydrolase	-
ACLV7A_RS02080 (SMIE22_04030)	-	401518..402522 (-)	1005	WP_411863456.1	NADP-dependent oxidoreductase	-
ACLV7A_RS02085 (SMIE22_04040)	-	402744..403175 (-)	432	WP_411863457.1	Rrf2 family transcriptional regulator	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24999.34 Da
• Isoelectric Point: 7.5762

>NTDB_id=1170275 ACLV7A_RS02060 WP_411863453.1 398447..399106(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis E22]
MIDFYFFLVGSILASFLGLVIDRFPEQSIIQPASHCDSCQTRLRPLDLIPILSQVLNRFRCRYCKAPYPIWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWLTFHLILMAFCGWNLVMVFFLILGIMAHFIDIRMGAGDFL
FLASCALVFSATELLILIQFASAMGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=1170275 ACLV7A_RS02060 WP_411863453.1 398447..399106(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis E22]
ATGATTGATTTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTTATTGACCGTTTTCCTGAGCA
ATCCATTATCCAACCTGCTAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCTATTCTCTCGC
AGGTGCTCAATCGCTTTCGCTGTCGCTACTGCAAGGCTCCTTATCCTATTTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGCTTGACCTTGGGTAT
CTACGACTTTCGTCATCAGGAATATCCCTTACTGGTCTGGCTGACTTTCCACCTAATCCTCATGGCTTTCTGTGGTTGGA
ATCTAGTCATGGTCTTCTTCCTTATCCTTGGAATCATGGCCCATTTTATCGATATCCGCATGGGCGCAGGGGATTTTCTC
TTTCTTGCTTCTTGCGCTCTCGTCTTTAGCGCGACCGAATTACTGATCTTGATTCAGTTTGCTTCTGCGATGGGAATTCT
AGCCTTTCTCCTACAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTCGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	93.151	100	0.932
cclA/cilC	Streptococcus pneumoniae D39	93.151	100	0.932
cclA/cilC	Streptococcus pneumoniae R6	93.151	100	0.932
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus pneumoniae TIGR4	89.041	100	0.89
cclA/cilC	Streptococcus mitis NCTC 12261	88.584	100	0.886