Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   ACLV7A_RS00120 Genome accession   NZ_OZ217344
Coordinates   22543..22779 (+) Length   78 a.a.
NCBI ID   WP_173213476.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis E22     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 20840..22006 22543..22779 flank 537


Gene organization within MGE regions


Location: 20840..22779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7A_RS00115 (SMIE22_00180) - 20840..22006 (+) 1167 WP_411863292.1 IS30 family transposase -
  ACLV7A_RS00120 (SMIE22_00190) comW 22543..22779 (+) 237 WP_173213476.1 sigma(X)-activator ComW Regulator

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9734.27 Da        Isoelectric Point: 7.2368

>NTDB_id=1170248 ACLV7A_RS00120 WP_173213476.1 22543..22779(+) (comW) [Streptococcus mitis isolate S. mitis E22]
MLKSIYEQMADFYRNIEEEYGTVFGDNFDWEHFHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLIMKQGFVAC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=1170248 ACLV7A_RS00120 WP_173213476.1 22543..22779(+) (comW) [Streptococcus mitis isolate S. mitis E22]
ATGCTAAAAAGTATTTATGAGCAGATGGCAGATTTTTATAGAAATATTGAAGAAGAGTATGGTACTGTATTTGGTGATAA
TTTTGACTGGGAACATTTTCATTTTAAATTTTTGATTTATTATTTAGTTAGATATGGCATTGGGTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGATAATGAAACAAGGTTTTGTTGCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus mitis SK321

85.897

100

0.859
  comW Streptococcus mitis NCTC 12261

85.714

98.718

0.846
  comW Streptococcus pneumoniae Rx1

82.051

100

0.821
  comW Streptococcus pneumoniae D39

82.051

100

0.821
  comW Streptococcus pneumoniae R6

82.051

100

0.821
  comW Streptococcus pneumoniae TIGR4

82.051

100

0.821

Multiple sequence alignment