Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   ACLV7Z_RS04840 Genome accession   NZ_OZ217343
Coordinates   981336..982685 (+) Length   449 a.a.
NCBI ID   WP_050090938.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis G22     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 976336..987685
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Z_RS04820 (SMIG22_09390) - 977244..978914 (+) 1671 WP_218774835.1 formate--tetrahydrofolate ligase -
  ACLV7Z_RS04825 (SMIG22_09400) - 979035..979322 (-) 288 WP_218774836.1 hypothetical protein -
  ACLV7Z_RS04830 (SMIG22_09410) mutY 979408..980583 (+) 1176 WP_218774837.1 A/G-specific adenine glycosylase -
  ACLV7Z_RS04835 (SMIG22_09420) micA 980639..981343 (+) 705 WP_050259789.1 response regulator YycF Regulator
  ACLV7Z_RS04840 (SMIG22_09430) micB 981336..982685 (+) 1350 WP_050090938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACLV7Z_RS04845 (SMIG22_09440) vicX 982687..983496 (+) 810 WP_218774838.1 MBL fold metallo-hydrolase Regulator
  ACLV7Z_RS04850 (SMIG22_09450) relB 983587..983829 (+) 243 WP_050223090.1 type II toxin-antitoxin system RelB family antitoxin -
  ACLV7Z_RS04855 (SMIG22_09460) - 983831..984085 (+) 255 WP_007284771.1 type II toxin-antitoxin system RelE family toxin -
  ACLV7Z_RS04860 (SMIG22_09470) - 984159..986042 (+) 1884 WP_218774839.1 Eco57I restriction-modification methylase domain-containing protein -
  ACLV7Z_RS04865 (SMIG22_09480) - 986152..987102 (+) 951 WP_000658133.1 Abi family protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51714.43 Da        Isoelectric Point: 4.9756

>NTDB_id=1170207 ACLV7Z_RS04840 WP_050090938.1 981336..982685(+) (micB) [Streptococcus mitis isolate S. mitis G22]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIRLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEEDYELRDLITQSPE
LLLDSQDINGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1170207 ACLV7Z_RS04840 WP_050090938.1 981336..982685(+) (micB) [Streptococcus mitis isolate S. mitis G22]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATTTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAGAATAGACGTGATAATATTCGATTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGACTAAATAGTATTCTGTTTTATATGACAGATGGGGT
CCTTGCGACCAATCGTCGGGGGCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGCTGGTTAAAGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAGACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGACATCAATGGGGAATATCTGAGCCTTCGAGTTCGCTTTGCCTTGATTCGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAGCGCGAACGGAGACTCTTCGTTT
CCAACGTTAGTCATGAGTTACGGACTCCTTTAACCAGCGTGAAATCTTATCTTGAAGCCTTGGATGAGGGAGCTTTGTGT
GAAACTGTAGCACCAGACTTCATCAAGGTGTCTCTGGACGAAACCAACCGTATGATGCGCATGGTGACCGATCTCCTTCA
TCTTTCACGGATTGATAACGCCACTAGTCACTTGGATGTGGAACTGATTAACTTCACTGCCTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCATGGTTTAGGCATTCCTAAGC
AGGATTTACCACGTATTTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTATCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGTAAGGGATCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(98-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.109

100

0.991
  vicK Streptococcus mutans UA159

69.652

89.532

0.624

Multiple sequence alignment