Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   ACLV65_RS00200 Genome accession   NZ_OZ217342
Coordinates   34773..35009 (+) Length   78 a.a.
NCBI ID   WP_000940045.1    Uniprot ID   E1LR49
Organism   Streptococcus mitis isolate S. mitis B22     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 33571..34122 34773..35009 flank 651


Gene organization within MGE regions


Location: 33571..35009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV65_RS00195 - 33571..34507 (-) 937 Protein_32 ISL3 family transposase -
  ACLV65_RS00200 (SMIB22_00360) comW 34773..35009 (+) 237 WP_000940045.1 sigma(X)-activator ComW Regulator

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9830.29 Da        Isoelectric Point: 6.2034

>NTDB_id=1170080 ACLV65_RS00200 WP_000940045.1 34773..35009(+) (comW) [Streptococcus mitis isolate S. mitis B22]
MLQNIYDQMTDFYDSIEEEYATFFGNSWDWEHFHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKMIMKQGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=1170080 ACLV65_RS00200 WP_000940045.1 34773..35009(+) (comW) [Streptococcus mitis isolate S. mitis B22]
ATGCTACAAAATATTTATGATCAGATGACTGATTTCTATGACAGTATCGAAGAAGAGTATGCTACTTTCTTTGGTAATAG
TTGGGACTGGGAACATTTTCATTTTAAATTTTTGATTTATTATTTAGTTAGATATGGTATTGGGTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAGATGATAATGAAACAAGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E1LR49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

79.487

100

0.795
  comW Streptococcus pneumoniae D39

79.487

100

0.795
  comW Streptococcus pneumoniae R6

79.487

100

0.795
  comW Streptococcus pneumoniae TIGR4

79.487

100

0.795
  comW Streptococcus mitis SK321

76.923

100

0.769
  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756

Multiple sequence alignment