Detailed information NTG1159876

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: QWI70_RS08435
• Genome accession: NZ_OX465025
• Coordinates: 1662832..1663521 (-)
• Length: 229 a.a.
• NCBI ID: WP_000516681.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate MRI Z2-329
• Function: repress comR expression (predicted from homology) Competence regulation

Genomic Context

Location: 1657832..1668521

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QWI70_RS08415	dnaI	1658635..1659537 (-)	903	WP_000843626.1	primosomal protein DnaI	-
QWI70_RS08420	-	1659534..1660709 (-)	1176	WP_000074512.1	DnaD domain protein	-
QWI70_RS08425	nrdR	1660709..1661188 (-)	480	WP_001203682.1	transcriptional regulator NrdR	-
QWI70_RS08430	-	1661337..1662842 (-)	1506	WP_000791112.1	HAMP domain-containing histidine kinase	-
QWI70_RS08435	covR	1662832..1663521 (-)	690	WP_000516681.1	response regulator transcription factor	Regulator
QWI70_RS08440	-	1663756..1664289 (-)	534	WP_000927543.1	YceD family protein	-
QWI70_RS08445	htpX	1664394..1665284 (-)	891	WP_000966817.1	zinc metalloprotease HtpX	-
QWI70_RS08450	-	1665305..1665859 (-)	555	WP_000537055.1	LemA family protein	-
QWI70_RS08455	rsmG	1665987..1666700 (+)	714	WP_000188792.1	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	-
QWI70_RS08460	-	1666715..1668094 (+)	1380	WP_000680112.1	potassium transporter TrkG	-

Sequence

Protein

• Length: 229 a.a.
• Molecular weight: 26547.55 Da
• Isoelectric Point: 4.8094

>NTDB_id=1159876 QWI70_RS08435 WP_000516681.1 1662832..1663521(-) (covR) [Streptococcus agalactiae isolate MRI Z2-329]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide

• Length: 690 bp

>NTDB_id=1159876 QWI70_RS08435 WP_000516681.1 1662832..1663521(-) (covR) [Streptococcus agalactiae isolate MRI Z2-329]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGTGGTA
GTTTCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-114)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (152-225)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Streptococcus salivarius strain HSISS4	79.476	100	0.795
covR	Lactococcus lactis subsp. lactis strain DGCC12653	66.228	99.563	0.659
vicR	Streptococcus mutans UA159	45.887	100	0.463
micA	Streptococcus pneumoniae Cp1015	43.478	100	0.437