Detailed information NTG1159725

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: OWO33_RS09195
• Genome accession: NZ_OX461090
• Coordinates: 1800023..1800709 (-)
• Length: 228 a.a.
• NCBI ID: WP_267257363.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate MRI Z2-336
• Function: repress comR expression (predicted from homology) Competence regulation

Genomic Context

Location: 1795023..1805709

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OWO33_RS09175	dnaI	1795826..1796728 (-)	903	WP_000843627.1	primosomal protein DnaI	-
OWO33_RS09180	-	1796725..1797900 (-)	1176	WP_000074512.1	DnaD domain protein	-
OWO33_RS09185	nrdR	1797900..1798379 (-)	480	WP_001203682.1	transcriptional regulator NrdR	-
OWO33_RS09190	-	1798528..1800033 (-)	1506	WP_000791116.1	HAMP domain-containing histidine kinase	-
OWO33_RS09195	covR	1800023..1800709 (-)	687	WP_267257363.1	response regulator transcription factor	Regulator
OWO33_RS09200	-	1800944..1801477 (-)	534	WP_000927543.1	YceD family protein	-
OWO33_RS09205	htpX	1801582..1802472 (-)	891	WP_000966817.1	zinc metalloprotease HtpX	-
OWO33_RS09210	-	1802493..1803047 (-)	555	WP_000537055.1	LemA family protein	-
OWO33_RS09215	rsmG	1803175..1803888 (+)	714	WP_000188795.1	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	-
OWO33_RS09220	-	1803903..1805282 (+)	1380	WP_000680112.1	potassium transporter TrkG	-

Sequence

Protein

• Length: 228 a.a.
• Molecular weight: 26448.42 Da
• Isoelectric Point: 4.8094

>NTDB_id=1159725 OWO33_RS09195 WP_267257363.1 1800023..1800709(-) (covR) [Streptococcus agalactiae isolate MRI Z2-336]
MGKKILIIEDEKNLARFVSLELLHEGYDVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMTA
RDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKREF
DLLNVLMTNMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide

• Length: 687 bp

>NTDB_id=1159725 OWO33_RS09195 WP_267257363.1 1800023..1800709(-) (covR) [Streptococcus agalactiae isolate MRI Z2-336]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATTTAA
TGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACAGCA
CGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGAAGA
ATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGTGGTAGTT
TCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAATTT
GATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATACGA
TGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAATCAT
ATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (151-224)

• Response regulator receiver domain (Response_reg) (5-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Streptococcus salivarius strain HSISS4	79.476	100	0.798
covR	Lactococcus lactis subsp. lactis strain DGCC12653	66.228	100	0.662
vicR	Streptococcus mutans UA159	45.887	100	0.465
micA	Streptococcus pneumoniae Cp1015	43.478	100	0.439