Detailed information NTG1159618

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: QOR59_RS08460
• Genome accession: NZ_OX460985
• Coordinates: 1665931..1666620 (-)
• Length: 229 a.a.
• NCBI ID: WP_283571952.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate MRI Z2-307
• Function: repress comR expression (predicted from homology) Competence regulation

Genomic Context

Location: 1660931..1671620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR59_RS08440	dnaI	1661734..1662636 (-)	903	WP_000843629.1	primosomal protein DnaI	-
QOR59_RS08445	-	1662633..1663808 (-)	1176	WP_000074512.1	DnaD domain protein	-
QOR59_RS08450	nrdR	1663808..1664287 (-)	480	WP_001203682.1	transcriptional regulator NrdR	-
QOR59_RS08455	-	1664436..1665941 (-)	1506	WP_000791116.1	HAMP domain-containing histidine kinase	-
QOR59_RS08460	covR	1665931..1666620 (-)	690	WP_283571952.1	response regulator transcription factor	Regulator
QOR59_RS08465	-	1666855..1667388 (-)	534	WP_000927543.1	YceD family protein	-
QOR59_RS08470	htpX	1667493..1668383 (-)	891	WP_000966819.1	zinc metalloprotease HtpX	-
QOR59_RS08475	-	1668404..1668958 (-)	555	WP_000537055.1	LemA family protein	-
QOR59_RS08480	rsmG	1669086..1669799 (+)	714	WP_000188792.1	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	-
QOR59_RS08485	-	1669814..1671193 (+)	1380	WP_283571953.1	potassium transporter TrkG	-

Sequence

Protein

• Length: 229 a.a.
• Molecular weight: 26489.52 Da
• Isoelectric Point: 4.8894

>NTDB_id=1159618 QOR59_RS08460 WP_283571952.1 1665931..1666620(-) (covR) [Streptococcus agalactiae isolate MRI Z2-307]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYGVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide

• Length: 690 bp

>NTDB_id=1159618 QOR59_RS08460 WP_283571952.1 1665931..1666620(-) (covR) [Streptococcus agalactiae isolate MRI Z2-307]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGTGGTA
GTTTCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGGTGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (152-225)

• Response regulator receiver domain (Response_reg) (5-114)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Streptococcus salivarius strain HSISS4	79.039	100	0.79
covR	Lactococcus lactis subsp. lactis strain DGCC12653	66.228	99.563	0.659
vicR	Streptococcus mutans UA159	45.455	100	0.459
micA	Streptococcus pneumoniae Cp1015	43.043	100	0.432