Detailed information NTG1159172

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: QOR48_RS01085
• Genome accession: NZ_OX460942
• Coordinates: 187936..188979 (+)
• Length: 347 a.a.
• NCBI ID: WP_223295592.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate MRI Z2-158
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 182936..193979

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR48_RS01075	-	186533..186898 (+)	366	WP_000285373.1	DUF1033 family protein	-
QOR48_RS01080	comYA	187071..188042 (+)	972	WP_000250808.1	competence type IV pilus ATPase ComGA	Machinery gene
QOR48_RS01085	comYB	187936..188979 (+)	1044	WP_223295592.1	competence type IV pilus assembly protein ComGB	Machinery gene
QOR48_RS01090	comYD	188976..189404 (+)	429	WP_000793381.1	competence type IV pilus minor pilin ComGD	Machinery gene
QOR48_RS01095	comGE	189376..189675 (+)	300	WP_001867089.1	competence type IV pilus minor pilin ComGE	-
QOR48_RS01100	comGF	189629..190090 (+)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	-
QOR48_RS01105	comGG	190068..190439 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	-
QOR48_RS01110	comYH	190554..191528 (+)	975	WP_001008570.1	class I SAM-dependent methyltransferase	Machinery gene
QOR48_RS01115	-	191560..192753 (+)	1194	WP_000047535.1	acetate kinase	-
QOR48_RS01120	-	192904..193110 (+)	207	WP_000798242.1	helix-turn-helix transcriptional regulator	-
QOR48_RS01125	-	193169..193306 (+)	138	WP_001867090.1	hypothetical protein	-
QOR48_RS01130	-	193347..193802 (+)	456	WP_000905674.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40005.70 Da
• Isoelectric Point: 9.9365

>NTDB_id=1159172 QOR48_RS01085 WP_223295592.1 187936..188979(+) (comYB) [Streptococcus agalactiae isolate MRI Z2-158]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDYYTDRMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLTFLVLIMIGLRHYLMPQLGENNFATS
LITNVPNIFLLLLAVVLIFSLIFYIVQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGVELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS

Nucleotide

• Length: 1044 bp

>NTDB_id=1159172 QOR48_RS01085 WP_223295592.1 187936..188979(+) (comYB) [Streptococcus agalactiae isolate MRI Z2-158]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTATTATACAGATAGGATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGACTTTTCTGGTGCTAATTATGATTGGTCTTAGGCATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGC
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTGTTCA
AAAGCGATTGTCGCGTATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTGTTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGCCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCTGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (218-338)

• Type II secretion system (T2SS), protein F (T2SSF) (33-150)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	61.877	98.271	0.608
comYB	Streptococcus mutans UA159	61.584	98.271	0.605
comYB	Streptococcus gordonii str. Challis substr. CH1	56.305	98.271	0.553
comGB/cglB	Streptococcus mitis NCTC 12261	54.925	96.542	0.53
comGB/cglB	Streptococcus mitis SK321	54.328	96.542	0.524
comGB/cglB	Streptococcus pneumoniae Rx1	53.433	96.542	0.516
comGB/cglB	Streptococcus pneumoniae D39	53.433	96.542	0.516
comGB/cglB	Streptococcus pneumoniae R6	53.433	96.542	0.516
comGB/cglB	Streptococcus pneumoniae TIGR4	53.433	96.542	0.516
comGB	Lactococcus lactis subsp. cremoris KW2	49.852	97.118	0.484