Detailed information NTG0115758

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SMUFR_RS02940
• Genome accession: NZ_CP007016
• Coordinates: 583750..585984 (+)
• Length: 744 a.a.
• NCBI ID: WP_002261915.1
• Uniprot ID: A0AAX1K0M7
• Organism: Streptococcus mutans UA159-FR
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 578750..590984

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUFR_RS02915 (SMUFR_0536)	-	579450..580469 (-)	1020	WP_002261920.1	GIY-YIG nuclease family protein	-
SMUFR_RS02920 (SMUFR_0537)	-	580515..581027 (-)	513	WP_002261919.1	HXXEE domain-containing protein	-
SMUFR_RS02925 (SMUFR_0538)	-	581116..582051 (-)	936	WP_002261918.1	polysaccharide deacetylase family protein	-
SMUFR_RS02930 (SMUFR_0539)	-	582190..582942 (+)	753	WP_002261917.1	lysophospholipid acyltransferase family protein	-
SMUFR_RS02935 (SMUFR_0540)	-	583083..583760 (+)	678	WP_002261916.1	helix-hairpin-helix domain-containing protein	-
SMUFR_RS02940 (SMUFR_0541)	comEC/celB	583750..585984 (+)	2235	WP_002261915.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SMUFR_RS02945 (SMUFR_0542)	-	586170..586796 (+)	627	WP_002261914.1	DUF805 domain-containing protein	-
SMUFR_RS02950 (SMUFR_0543)	holA	586964..588004 (+)	1041	WP_002261913.1	DNA polymerase III subunit delta	-
SMUFR_RS02955 (SMUFR_0544)	sodA	588151..588762 (+)	612	WP_002261912.1	superoxide dismutase SodA	-
SMUFR_RS10220 (SMUFR_0545)	-	589314..590369 (+)	1056	WP_011074536.1	serine hydrolase	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 85545.98 Da
• Isoelectric Point: 10.0891

>NTDB_id=115758 SMUFR_RS02940 WP_002261915.1 583750..585984(+) (comEC/celB) [Streptococcus mutans UA159-FR]
MLIRFFPLKPIYLAFLTVLLYFCIHCFSFLPVGLFILALVFLVFQYDRQICIKTLLFLLPFAAFFFYFHQKRQSEYQIVP
RQVQKLIIIPDTLSVNGDNLSFRAKSGHWTYQVFYKLKSETEKHYFEQLWQTAEIQVTADVVEAEEQRNFKGFDYRNYLK
MQGIYRIVNVTDIKTIKLSSKRFWFARLHEWRRRALVSIQSKFPDPMKHYMTGLLFGYLDKSFDEMNAIYSSLGIIHLFA
LSGMQVSFFIGKFRYLGLRLGIRQEYMNAIQLPFSLLYAGLTGFAVSVVRSLIQGNLTHFGFKKQDNFALTLFVMFFLIP
NFLLTTGGVLSFAYAFILIMIDFETLSLLKRILFQTFSLSLGILPLLMWYFSSFQPLSILLTILFSFIFDNLMLPFLTLA
YFLSPFVSLACFNPAFRLLERIIVQIHLIFSRPFILGSPTLPILLLLLCLLALLYDFRQKKRVVLVLSSILALLFFISKN
PLTNEVTIVDIGQGDSILLRDISSKTILIDVGGKVTFGQTDKWRRRISDTNAEKTLIPYLKSRGIDKIDQLVLTHTDTDH
MGDMEVVAKAFHVGEVLVSPGSLTKANFVSKLRRMKVKVHITKPGETLSIMGSHLQVLYPLKIGDGGNNDSIVLYGRLLG
LNFLFTGDLEKEGEAELLKTYPNLKVDVLKAGHHGSKGSSSPELLAQIEPKIALISAGKNNRYKHPHQETLDRFAQIKSR
IYRTDQEGAIRFKGLKHWQIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=115758 SMUFR_RS02940 WP_002261915.1 583750..585984(+) (comEC/celB) [Streptococcus mutans UA159-FR]
GTGTTGATTAGGTTTTTTCCTCTCAAACCAATCTATTTAGCCTTTTTAACTGTTTTGCTTTATTTTTGTATTCACTGCTT
TTCTTTTTTGCCAGTTGGCCTATTTATTTTAGCTTTAGTCTTTCTTGTTTTTCAATATGATAGGCAAATCTGTATCAAAA
CACTTTTGTTTTTATTGCCTTTTGCCGCTTTCTTTTTCTATTTTCACCAAAAAAGGCAAAGCGAGTATCAAATAGTACCC
AGACAGGTTCAAAAGTTAATTATCATTCCAGATACGCTTAGTGTCAATGGAGATAACTTAAGTTTTCGAGCAAAATCAGG
TCATTGGACTTATCAGGTCTTTTATAAATTAAAATCTGAAACAGAGAAACATTATTTTGAACAATTATGGCAGACAGCAG
AAATTCAAGTGACAGCAGATGTTGTAGAAGCAGAAGAGCAGCGTAATTTCAAGGGATTCGATTATAGAAACTATTTAAAG
ATGCAGGGAATTTACCGAATTGTTAATGTTACAGACATTAAAACAATTAAACTGAGTTCTAAACGCTTCTGGTTTGCTCG
TTTGCATGAATGGCGACGAAGAGCTTTGGTATCTATTCAGTCAAAATTTCCAGACCCCATGAAACACTATATGACTGGTC
TGCTTTTTGGCTATTTAGATAAATCCTTTGATGAAATGAATGCTATTTATTCTAGCTTAGGTATTATTCACCTTTTTGCT
TTGTCAGGTATGCAGGTTAGTTTTTTCATTGGGAAATTTCGTTATTTGGGCTTGCGTTTAGGTATTAGACAGGAATACAT
GAATGCTATTCAGCTGCCCTTTTCTTTGCTTTATGCTGGTTTGACTGGCTTTGCAGTATCCGTTGTGCGTAGTTTGATTC
AAGGTAATCTTACTCATTTTGGTTTTAAAAAGCAGGATAACTTTGCTCTAACCTTATTTGTTATGTTTTTCCTGATACCC
AATTTCTTATTAACAACAGGAGGTGTGCTTAGTTTTGCCTATGCTTTTATTCTAATCATGATTGATTTTGAGACTTTGTC
ACTCTTAAAGCGGATTCTATTTCAAACCTTTTCTCTTTCTTTAGGGATTTTACCGTTATTGATGTGGTATTTTAGCAGTT
TTCAGCCCTTGTCTATCCTATTAACTATCCTCTTTTCTTTTATTTTTGATAACTTGATGTTGCCTTTTTTGACACTTGCT
TATTTTCTGTCACCTTTTGTATCACTTGCCTGCTTCAATCCAGCTTTTAGATTATTAGAAAGAATAATTGTTCAAATTCA
CCTAATCTTTAGTCGTCCTTTTATTTTGGGCAGTCCGACTTTGCCTATTCTCTTACTTTTATTGTGCCTTTTAGCTTTAC
TCTATGATTTTCGTCAGAAAAAAAGGGTAGTGTTAGTACTTAGTAGCATTCTCGCCCTGTTATTTTTCATCAGTAAAAAT
CCTTTGACTAATGAAGTGACTATTGTTGATATTGGTCAGGGGGATAGTATTCTTCTTCGGGATATCAGCAGTAAGACTAT
TTTAATTGATGTAGGAGGAAAAGTAACTTTTGGACAGACTGATAAATGGCGGCGGCGTATCAGTGATACTAATGCTGAAA
AGACTTTGATTCCCTATCTCAAAAGCAGAGGCATTGATAAGATTGACCAATTGGTTTTGACTCATACTGACACGGATCAT
ATGGGAGATATGGAAGTGGTGGCAAAGGCCTTTCATGTTGGGGAAGTTTTAGTTAGTCCAGGCAGTTTAACTAAGGCAAA
TTTTGTCAGTAAATTGAGAAGAATGAAAGTTAAGGTACACATCACTAAGCCAGGGGAGACATTATCCATTATGGGGAGTC
ATTTACAGGTACTCTATCCGTTGAAAATAGGTGATGGTGGTAATAATGACTCTATCGTTCTTTATGGACGTTTGCTAGGC
TTAAATTTTCTCTTTACAGGAGATTTGGAAAAAGAAGGAGAAGCAGAATTGCTAAAGACTTATCCCAATTTAAAAGTTGA
TGTCTTAAAAGCTGGACATCATGGTTCAAAAGGTTCTTCTTCACCTGAATTATTAGCTCAAATAGAGCCTAAAATTGCTC
TTATCTCGGCAGGAAAGAACAATCGTTATAAACATCCCCATCAGGAGACACTGGACAGATTTGCGCAAATAAAAAGTCGG
ATTTATCGGACGGATCAAGAGGGTGCCATTCGTTTTAAGGGTCTTAAGCATTGGCAGATTGAGACTGTGCGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-174)

• Competence protein (Competence) (214-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	51.213	99.731	0.511
comEC/celB	Streptococcus mitis SK321	51.282	99.597	0.511
comEC/celB	Streptococcus pneumoniae TIGR4	50.806	100	0.508
comEC/celB	Streptococcus pneumoniae Rx1	50.134	100	0.501
comEC/celB	Streptococcus pneumoniae D39	50.134	100	0.501
comEC/celB	Streptococcus pneumoniae R6	50.134	100	0.501
comEC	Lactococcus lactis subsp. cremoris KW2	46.309	100	0.464